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Environmental toxicology

Author: Sigmund F Zakrzewski
Publisher: New York : Oxford University Press, 2002.
Edition/Format:   Print book : English : 3rd edView all editions and formats
Summary:

The principles of environmental toxicology are clearly presented here for university students and professionals in related fields. The book explains basic concepts such as the fate of toxic chemicals  Read more...

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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Sigmund F Zakrzewski
ISBN: 0195148118 9780195148114
OCLC Number: 46936030
Notes: Revised edition of: Principles of environmental toxicology. 2nd ed. 1997.
Description: xvii, 334 pages : illustrations ; 24 cm
Contents: 1. Environment: Past and Present. Historical Perspective. Present State of the World. The United Nations Conference on Environment and Development: The Earth Summit. Antienvironmental Movements in the United States. Rio Plus Five. The Impact of Global Trade on the Environment --
2. Review of Pharmacologic Concepts. Dose-Response Relationship. The Concept of Receptors. Mode of Entry of Toxins. Translocation of Xenobiotics --
3. Metabolism of Xenobiotics. Phases of Metabolism. Phase 1 --
Biotransformations. Disposition of Epoxides. Phase 2 --
Conjugations. Glutathione. Induction and Inhibition of P-450 Isozymes. Activation of Precarcinogens --
4. Factors that Influence Toxicity. Selective Toxicity. Metabolic Pathways. Enzyme Activity. Xenobiotic-Metabolizing Systems. Toxicity Tests in Animals. Individual Variations in Response to Xenobiotics --
5. Chemical Carcinogenesis and Mutagenesis. Environment and Cancer. Multistage Development of Cancer. Types of Carcinogens. Review of DNA and Chromosomal Structure. Mutagenesis. Interaction of Chemicals with DNA. Xenoestrogens and Breast Cancer. Carcinogenic Effect of Low-Frequency Electromagnetic Fields. DNA Repair Mechanism. Oncogenes and Tumor Supressor Genes --
6. Endocrine Disrupters. Historical Perspectives. Hormonal Imbalance. Properties of Endocrine Disrupters. Environmental and Health Impact of Endocrine Disrupters --
7. Risk Assessment. Hazard Assessment. Dose-Response Assessment. Exposure Assessment. Risk Characterization. Critique of Risk Assessment. Risk Assessment of Endocrine Disrupters. Ecological Risk Assessment. The Principle of Precautionary Action --
8. Occupational Toxicology. Threshold Limit Values and Biological Exposure Indices. Respiratory Toxicity. Irritation of Airways and Edema. Pulmonary Fibrosis. Pulmonary Neoplasia. Allergic Responses. Nephrotoxins. Liver Damage. Other Toxic Responses --
9. Air Pollution. Pollutant Cycles. Urban Pollutants: Their Sources and Biological Effects. Trends and Present Status of Air Quality. Pollution by Motor Vehicles. Pollution by Industrial Chemicals. Pollution by Incinerators. Tall Stacks and Their Role in Transport of Pollutants. Indoor Air Pollution --
10. Pollution of the Atmosphere. This Earth's Atmosphere. Formation and Sustenance of Stratospheric Ozone. Depletion of Stratospheric Ozone. Emission of CO[subscript 2] and Models of Climatic Changes. Current Developments. The Effects of Atmospheric Changes on Human Health --
11. Water and Land Pollution. Freshwater Reserves. Nitrogen Overload. Transport of Water Pollutants. Urban Pollutants. Lead Pollution. Soil Erosion. Nutrients and Pesticides. Alternative Agriculture. Genetically Modified Crops. Wetlands and Estuaries. Industrial Pollutants. Pollution of Groundwater. Airborne Water and Land Pollution --
12. Pollution Control. Clean-Coal Technology. Control of Mobile-Source Emission. Control of Nitrogen Oxides. Energy Conservation. Wastewater Treatment. Waste Disposal and Recycling. Hazardous Waste --
13. Radioactive Pollution. Ionizing Radiation. Measurement of Radioactivity. Sources of Radiation. Health and Biological Effects of Radiation. Nuclear Energy --
14. Population, Environment, and Women's Issues. Present Trends in Population Growth. Effect of Overpopulation on the Environment. Overpopulation, Urban Sprawl, and Public Health. International Cooperation on Population Issues --
15. Regulatory Policies and International Treaties. The National Environmental Policy Act. Environmental Regulatory Framework. EPA and Its Responsibilities. OSHA and Its Responsibilities. Miscellaneous Environmental Acts and Treaties.
Responsibility: Sigmund F. Zakrzewski.
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