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Environmental Toxicology.

Author: Zahrzewski.; Sigmund F Zakrzewski
Publisher: Cary : Oxford University Press, 2002.
Edition/Format:   eBook : Document : English : 3rd edView all editions and formats
Summary:
The fundamental principles of environmental toxicology are clearly presented here for university students and professionals in related fields. This book consists of two parts. In the first part basic metabolic, physiological, and pharmacological concepts are used to explain the fate of toxic chemicals in the body, with emphasis on carcinogenesis and mutagenesis. This part also contains a chapter on chemicals  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Zahrzewski.
Environmental Toxicology.
Cary : Oxford University Press, ©2002
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Zahrzewski.; Sigmund F Zakrzewski
ISBN: 9781602569836 1602569835
OCLC Number: 935262000
Notes: Wastewater Treatment.
Description: 1 online resource (353 pages)
Contents: 1. ENVIRONMENT: PAST AND PRESENT; Historical Perspective; Present State of the World; The United Nations Conference on Environment and Development: The Earth Summit; Antienvironmental Movements in the United States; Rio Plus Five; The Impact of Global Trade on the Environment; 2. REVIEW OF PHARMACOLOGIC CONCEPTS; Dose-Response Relationship; The Concept of Receptors; Mode of Entry of Toxins; Translocation of Xenobiotics; 3. METABOLISM OF XENOBIOTICS; Phases of Metabolism; Phase 1-Biotransformations; Disposition of Epoxides; Phase 2-Conjugations; Glutathione. Induction and Inhibition of P-450 IsozymesActivation of Precarcinogens; 4. FACTORS THAT INFLUENCE TOXICITY; Selective Toxicity; Metabolic Pathways; Enzyme Activity; Xenobiotic-Metabolizing Systems; Toxicity Tests in Animals; Individual Variations in Response to Xenobiotics; 5. CHEMICAL CARCINOGENESIS AND MUTAGENESIS; Environment and Cancer; Multistage Development of Cancer; Types of Carcinogens; Review of DNA and Chromosomal Structure; Mutagenesis; Interaction of Chemicals with DNA; Xenoestrogens and Breast Cancer; Carcinogenic Effect of Low-Frequency Electromagnetic Fields. DNA Repair MechanismOncogenes and Tumor Supressor Genes; 6. ENDOCRINE DISRUPTERS; Historical Perspectives; Hormonal Imbalance; Properties of Endocrine Disrupters; Environmental and Health Impact of Endocrine Disrupters; 7. RISK ASSESSMENT; Hazard Assessment; Dose-Response Assessment; Exposure Assessment; Risk Characterization; Critique of Risk Assessment; Risk Assessment of Endocrine Disrupters; Ecological Risk Assessment; The Principle of Precautionary Action; 8. OCCUPATIONAL TOXICOLOGY; Threshold Limit Values and Biological Exposure Indices; Respiratory Toxicity. Irritation of Airways and EdemaPulmonary Fibrosis; Pulmonary Neoplasia; Allergic Responses; Nephrotoxins; Liver Damage; Other Toxic Responses; 9. AIR POLLUTION; Pollutant Cycles; Urban Pollutants: Their Sources and Biological Effects; Trends and Present Status of Air Quality; Pollution by Motor Vehicles; Pollution by Industrial Chemicals; Pollution by Incinerators; Tall Stacks and Their Role in Transport of Pollutants; Indoor Air Pollution; 10. POLLUTION OF THE ATMOSPHERE; The Earth's Atmosphere; Formation and Sustenance of Stratospheric Ozone; Depletion of Stratospheric Ozone. Emission of CO[sub(2)] and Models of Climatic ChangesCurrent Developments; The Effects of Atmospheric Changes on Human Health; 11. WATER AND LAND POLLUTION; Freshwater Reserves; Nitrogen Overload; Transport of Water Pollutants; Urban Pollutants; Lead Pollution; Soil Erosion; Nutrients and Pesticides; Alternative Agriculture; Genetically Modified Crops; Wetlands and Estuaries; Industrial Pollutants; Pollution of Groundwater; Airborne Water and Land Pollution; 12. POLLUTION CONTROL; Clean-Coal Technology; Control of Mobile-Source Emission; Control of Nitrogen Oxides; Energy Conservation.

Abstract:

The fundamental principles of environmental toxicology are clearly presented here for university students and professionals in related fields. This book consists of two parts. In the first part basic metabolic, physiological, and pharmacological concepts are used to explain the fate of toxic chemicals in the body, with emphasis on carcinogenesis and mutagenesis. This part also contains a chapter on chemicals disrupting the endocrine system and a chapter on risk assessment and the precautionary principle. The second section deals with specific environmental problems - air pollution, alteration.

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