コンテンツへ移動
Enzyme inhibition in drug discovery and development : the good and the bad 資料のプレビュー
閉じる資料のプレビュー
確認中…

Enzyme inhibition in drug discovery and development : the good and the bad

著者: Chuang Lu; A P Li
出版: Hoboken, N.J. : Wiley, ©2010.
エディション/フォーマット:   書籍 : Englishすべてのエディションとフォーマットを見る
データベース:WorldCat
概要:
"Offering a unique approach that includes both the pharmacologic and pharmacokinetic aspects of enzyme inhibition, Enzyme Inhibition in Drug Discovery and Development examines the scientific concepts and experimental approaches related to enzyme inhibition as applied in drug discovery and drug development." "Through this focused, single-source reference on the fundamentals of drug discovery and development,  続きを読む
評価:

(まだ評価がありません) 0 件のレビュー - 是非あなたから!

件名:
関連情報:

 

オンラインで入手

この資料へのリンク

オフラインで入手

&AllPage.SpinnerRetrieving; この資料の所蔵館を検索中…

詳細

資料の種類: インターネット資料
ドキュメントの種類: 図書, インターネットリソース
すべての著者/寄与者: Chuang Lu; A P Li
ISBN: 9780470281741 047028174X
OCLC No.: 318292649
物理形態: xiii, 854 pages, [8] pages of plates : illustrations (some color) ; 25 cm
コンテンツ: The drug discovery process / Gerald T. Miwa --
Medicinal chemistry of the optimization of enzyme inhibitors / Geraldine Harriman, Amy Elder, and Indranath Ghosh --
Bioanalytical technologies in drug discovery / Jing-Tao Wu --
Safety biomarkers in drug development : emerging trends and implications / Eric R. Fedyk --
The role of drug metabolism in drug discovery / Tonika Bohnert and Liang-Shang Gan --
Applied pharmacokinetics in drug discovery and development / Hua Yang [and others] --
Enzyme inhibition and inactivation : cytochrome P450 enzymes / R. Scott Obach --
Cytochrome P450 induction / Edward L. LeCluyse [and others] --
Inhibition of drug-metabolizing enzymes in gastrointestinal tract and its influence on the drug-drug interaction prediction / Aleksandra Galetin and J. Brian Houston --
Enzyme inhibition in various in vitro systems / Ping Zhao --
Cytochrome P450 degradation and its clinical relevance / Mingxiang Liao [and others] --
Complexities of working with UDP-glucuronosyltransferases (UGTs) : focus on enzyme inhibition / Michael B. Fisher. Evaluation of inhibitors of drug metabolism in human hepatocytes / Albert P. Li and Chuang Lu --
Grapefruit juice and its constituents as new esterase inhibitors / Suresh K. Balani --
Transporter-xenobiotic interactions : an important aspect of drug development studies / Gang Luo, Richard Ridgewell, and Thomas Guenthner --
Polymorphisms of drug transporters and their clinical implications / Cindy Q. Xia and Johnny J. Yang --
Clinical drug interactions due to metabolic inhibition : prediction, assessment, and interpretation / Lisa L. von Moltke and David J. Greenblatt --
Predicting interindividual variability of metabolic drug-drug interactions : identifying the causes and accounting for them using a systems approach / Amin Rostami-Hodjegan --
NF-kB : mechanism, tumor biology, and inhibitors / Lenny Dang --
G-protein-coupled receptors as drug targets / Wenyan Miao and Lijun Wu --
Pharmacological modulation of ion channels for the treatment of chronic pain / Yi Liu and Ning Qin --
Targeting the mTOR pathway for tumor therapeutics / Wei Chen --
HIV-1 protease inhibitors as antiretroviral agents / Sergei V. Gulnik, Elena Afonina, and Michael Eissenstat.
責任者: edited by Chuang Lu, Albert P. Li.

概要:

This book covers the science and approaches of enzyme inhibition applied in drug discovery and drug development, including both pharmacology and pharmacokinetic aspects of enzyme inhibition.  続きを読む

レビュー

編集者のレビュー

出版社によるあらすじ

"The description of each topic is clear, well organized and informative, making the book a useful or even essential high-level handbook." (ChemMedChem, November 2010)

 
ユーザーレビュー
GoodReadsのレビューを取得中…
DOGObooksのレビューを取得中…

タグ

すべてのユーザーのタグ (1)

人気のタグを表示: タグリスト | タグクラウド

リクエストの確認

あなたは既にこの資料をリクエストしている可能性があります。このリクエストを続行してよろしければ、OK を選択してください。

リンクデータ


<http://www.worldcat.org/oclc/318292649>
library:oclcnum"318292649"
library:placeOfPublication
library:placeOfPublication
owl:sameAs<info:oclcnum/318292649>
rdf:typeschema:Book
schema:about
schema:about
schema:about
schema:about
schema:about
schema:about
schema:about
schema:about
schema:about
schema:about
schema:contributor
schema:contributor
schema:copyrightYear"2010"
schema:datePublished"2010"
schema:description"The drug discovery process / Gerald T. Miwa -- Medicinal chemistry of the optimization of enzyme inhibitors / Geraldine Harriman, Amy Elder, and Indranath Ghosh -- Bioanalytical technologies in drug discovery / Jing-Tao Wu -- Safety biomarkers in drug development : emerging trends and implications / Eric R. Fedyk -- The role of drug metabolism in drug discovery / Tonika Bohnert and Liang-Shang Gan -- Applied pharmacokinetics in drug discovery and development / Hua Yang [and others] -- Enzyme inhibition and inactivation : cytochrome P450 enzymes / R. Scott Obach -- Cytochrome P450 induction / Edward L. LeCluyse [and others] -- Inhibition of drug-metabolizing enzymes in gastrointestinal tract and its influence on the drug-drug interaction prediction / Aleksandra Galetin and J. Brian Houston -- Enzyme inhibition in various in vitro systems / Ping Zhao -- Cytochrome P450 degradation and its clinical relevance / Mingxiang Liao [and others] -- Complexities of working with UDP-glucuronosyltransferases (UGTs) : focus on enzyme inhibition / Michael B. Fisher."@en
schema:description"Evaluation of inhibitors of drug metabolism in human hepatocytes / Albert P. Li and Chuang Lu -- Grapefruit juice and its constituents as new esterase inhibitors / Suresh K. Balani -- Transporter-xenobiotic interactions : an important aspect of drug development studies / Gang Luo, Richard Ridgewell, and Thomas Guenthner -- Polymorphisms of drug transporters and their clinical implications / Cindy Q. Xia and Johnny J. Yang -- Clinical drug interactions due to metabolic inhibition : prediction, assessment, and interpretation / Lisa L. von Moltke and David J. Greenblatt -- Predicting interindividual variability of metabolic drug-drug interactions : identifying the causes and accounting for them using a systems approach / Amin Rostami-Hodjegan -- NF-kB : mechanism, tumor biology, and inhibitors / Lenny Dang -- G-protein-coupled receptors as drug targets / Wenyan Miao and Lijun Wu -- Pharmacological modulation of ion channels for the treatment of chronic pain / Yi Liu and Ning Qin -- Targeting the mTOR pathway for tumor therapeutics / Wei Chen -- HIV-1 protease inhibitors as antiretroviral agents / Sergei V. Gulnik, Elena Afonina, and Michael Eissenstat."@en
schema:exampleOfWork<http://worldcat.org/entity/work/id/795011628>
schema:inLanguage"en"
schema:name"Enzyme inhibition in drug discovery and development : the good and the bad"@en
schema:publisher
schema:reviews
rdf:typeschema:Review
schema:itemReviewed<http://www.worldcat.org/oclc/318292649>
schema:reviewBody""Offering a unique approach that includes both the pharmacologic and pharmacokinetic aspects of enzyme inhibition, Enzyme Inhibition in Drug Discovery and Development examines the scientific concepts and experimental approaches related to enzyme inhibition as applied in drug discovery and drug development." "Through this focused, single-source reference on the fundamentals of drug discovery and development, researchers in drug metabolism and pharmacokinetics (DMPK) will learn and appreciate target biology in drug discovery; discovery biologists and medical chemists will also broaden their understanding of DMPK."--Jacket."
schema:url
schema:workExample

Content-negotiable representations

ウインドウを閉じる

WorldCatにログインしてください 

アカウントをお持ちではないですか?簡単に 無料アカウントを作成することができます。.