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Epithelial polarity

Author: Gerard Apodaca; Luciana I Gallo
Publisher: San Rafael, Calif. : Morgan & Claypool, ©2013.
Series: Colloquium digital library of life sciences.; Colloquium series on building blocks of the cell, # 2.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Epithelial cells exhibit an apical-basolateral axis of polarity that is generated during embryogenesis, is maintained throughout adult life in the face of constant cell regeneration, and is perturbed in several epithelial-associated diseases. We examine the structural and functional organization of epithelial tissues, as well as the events critical for generating epithelial asymmetry including vectorial trafficking  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Apodaca, Gerard.
Epithelial Polarity.
San Rafael : Biota Publishing, ©2013
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Gerard Apodaca; Luciana I Gallo
ISBN: 9781615043996 1615043993 9781615043989 1615043985
OCLC Number: 894920740
Notes: Part of: Colloquium digital library of life sciences.
Series from website.
Description: 1 online resource (76 pages) : illustrations, digital file.
Contents: Epithelial Polarity; Colloquium Digital Library of Life Sciences; Colloquium Series on Building Blocks of the Cell: Cell Structure and Function; Abstract; Keywords; Contents; Chapter 1: Introduction; Chapter 2: Epithelial Cell Organization and Asymmetry; 2.1 ORGANIZATION AND STRUCTURE OF EPITHELIAL CELLS; 2.2 PLASMA MEMBRANE ASYMMETRY; 2.2.1 Apical Membrane Domain; 2.2.2 Lateral Membrane Domain; 2.2.3 The Basal Membrane; 2.3 MEMBRANE ORGANELLE AND CYTOSKELETAL ASYMMETRY; Chapter 3: Generation and Maintenance of Epithelial Polarity; 3.1 MODEL SYSTEMS TO STUDY EPITHELIAL POLARITY. 3.2 VECTORIAL TRAFFICKING PATHWAYS IN POLARIZED EPITHELIAL CELLS3.2.1 Biosynthetic Pathways; 3.2.2 Endocytic Pathways; 3.3 THE MACHINERY FOR VECTORIAL SORTING AND TRANSPORT OF PROTEINS; 3.3.1 Sorting of Basolateral Membrane Proteins; 3.3.2 Sorting of Apical Membrane Proteins; 3.3.3 Transport Mechanisms and Membrane Fusion; 3.4 ROLE OF POLARITY COMPLEXES AND SIGNALING MACHINERY IN EPITHELIAL POLARIZATION; 3.5 FUNCTION OF CELL-CELL AND CELL-MATRIX INTERACTIONS IN EPITHELIAL POLARIZATION; 3.6 BIOGENESIS OF LUMINAL AND BASOLATERAL MEMBRANE DOMAINS; 3.6.1 Lumen Formation. 3.6.2 Formation of the Basolateral Domain3.7 COMPLETION OF EPITHELIAL MORPHOGENESIS; 3.7.1 Brush Border Morphogenesis; 3.7.2 Ciliogenesis and Membrane Traffic; 3.8 GENERATION OF CELLULAR ASYMMETRY DURING DEVELOPMENT; Chapter 4: Diseases that Result from Defects in Epithelial Polarity; 4.1 MUTATIONS THAT AFFECT SORTING AND TRAFFICKING OF MEMBRANE PROTEINS; 4.2 MUTATIONS IN THE POLARIZED SORTING/ TRAFFICKING MACHINERY; 4.3 DEFECTS IN JUNCTION-ASSOCIATED PROTEINS; 4.4 CILIOPATHIES; 4.5 CANCER AND EPITHELIAL POLARITY; Acknowledgments; References; Author Biographies.
Series Title: Colloquium digital library of life sciences.; Colloquium series on building blocks of the cell, # 2.
Responsibility: Gerard Apodaca and Luciana I. Gallo.

Abstract:

Epithelial cells exhibit an apical-basolateral axis of polarity that is generated during embryogenesis, is maintained throughout adult life in the face of constant cell regeneration, and is perturbed  Read more...

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