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The epothilones : an outstanding family of anti-tumour agents : from soil to the clinic

Author: Karl-Heinz Altmann
Publisher: Wien ; New York : Springer, ©2009.
Series: Fortschritte der Chemie organischer Naturstoff, 90.
Edition/Format:   Print book : EnglishView all editions and formats
Database:WorldCat
Summary:

Epothilones have received unusual attention over the years. They are novel antitumor drugs which very much like their predecessor paclitaxel (Taxol) act via microtubule stabilization.

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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Karl-Heinz Altmann
ISBN: 9783211782064 3211782060
OCLC Number: 310153763
Description: viii, 260 pages : illustrations (some color) ; 24 cm.
Contents: General aspects / G. Höfle --
Biosynthesis and heterologous production of epothilones / R. Müller --
Total synthesis of epothilones A-F / J. Mulzer and K. Prantz --
Semisynthetic derivatives of epothilones / K.H. Altmann --
Preclinical pharmacology and structure-activity studies of epothilones / K.H. Altmann --
Clinical studies with epothilones / K.H. Altmann.
Series Title: Fortschritte der Chemie organischer Naturstoff, 90.
Responsibility: authors, K.H. Altmann [and others].
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