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Epstein-Barr virus and human disease, 1988

Author: D V Ablashi; International Association for Research on Epstein-Barr Virus and Associated Diseases.
Publisher: Clifton, N.J. : Humana Press, ©1989.
Series: Experimental biology and medicine (Clifton, N.J.)
Edition/Format:   Print book : Conference publication : EnglishView all editions and formats
Summary:

The major target cell for EBV infection has now been conclusively identified as the complement receptor-type 2 (CR2), the Cd/Cdg 3 3 receptor on B lymphocyte. It is apparent, however, that other  Read more...

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Genre/Form: Congresses
Conference papers and proceedings
Material Type: Conference publication
Document Type: Book
All Authors / Contributors: D V Ablashi; International Association for Research on Epstein-Barr Virus and Associated Diseases.
ISBN: 0896031659 9780896031654
OCLC Number: 20016316
Notes: Papers from the Third International Symposium on Epstein-Barr Virus and Associated Malignant Diseases held in Rome in 1988 under the auspices of the International Association for Research on Epstein-Barr Virus and Associated Diseases.
Description: xxvii, 522 pages : illustrations ; 24 cm.
Contents: I. Cellular and Molecular Biology of EBV.- Epstein-Barr Virus Transformation of B Lymphocytes: Molecular Pathogenesis.- Role of the ZEBRA Protein in the Switch Between Epstein-Barr Virus Latency and Replication.- DNA:EBNA-1 Interactions and Latency of Epstein-Barr Virus.- The EBV DR Enhancer Contains Two Functionally Different Domains: A and B.- Identification of the Gene Product Encoded by the notl Repeats of the Genome.- Effect of the BZLF 1 Transactivator on Different Classes of EBV Promoters.- EBNA Expression and CpG Methylation of Viral DNA in EBV Associated Tumors.- Transcription and Protein Expression Pattern of EBV in Freshly Infected Lymphoid Cells.- Characterization of a cDNA of Epstein-Barr Virus DNase Gene.- The 5' Flanking Region of the Gene for EBNA-2 Contains a Cell Type Specific cis-Acting Regulatory Element that Activates Transcription in Transfected B-Cells.- Establishment and Characterization of a Tumor Cell Line from Nasopharyngeal Carcinoma Tissue.- II. Molecular Pathobiology of EBV Infections.- EBV DNA Structure and Expression in EBV-Induced Proliferations.- The Role of Differentially Expressed EB-Viral and Cellular Genes for Development of Virus-Related Tumors and Possibilities of the Control of These Diseases.- Detection of Proteins Binding to the EBV EBNA-2 Promoter.- Anti EBNA-1 Protein Induced with TPA.- Characterization of the EBV Alkaline Exonuclease Expressed in a Recombinant Prokaryotic System.- Immunocytochemistry of EBV Envelope Glycoproteins on Freeze-Fractured Nuclear 125 Membranes of Virus Producer Cells.- Detection of a Transformation-Incompetent Epstein-Barr Virus Genotype in a Seronegative Host.- Propagation and Cytogenetic Analysis of NPC Biopsies in Nude Mice: Evidence for a Translocation in Chromosome #8 AT 8q 24, Which Is the Localization of the c-myc Gene.- Epstein-Barr Virus Gene Expression in Lymphomas Induced by the Virus in the Cottontop Tamarin.- The DNA Demethylating Agent 5-Azacytidine Induces the Expression of EBNA 2-6 and LMP in Burkitt Lymphoma Lines.- Epstein-Barr Virus mRNA Expression in Biopsies of Lymphoma Induced by the Virus in Cottontop Tamarin.- Establishment of Salivary Gland Epithelial Cell Lines from Patients with Sjogren's Syndrome and Normal Individual.- The Transforming Activity of a Nasopharyngeal Carcinoma-Derived Epstein-Barr Virus Isolate.- III. Immunological Aspects of EBV Infections.- Immune Control Mechanisms over EBV Infection.- Epstein-Barr Virus Infection and Immunoregulation.- Helper T Lymphocyte Proliferation is Stimulated by the Presence of EBV-Carrying B Lymphocytes.- Role of the Recognition of Virion Antigens in the T-Cell Mediated Inhibition of EBV-Induced B-Cell Transformation.- An Analysis of the Cytotoxic T-Cell Response of A- and B- Type EB Virus.- The Immune Response to Glycine-Rich Sequences of Epstein-Barr Nuclear Antigen-1 (EBNA-1) in Autoimmunity: B and T Cell Epitopes.- Cytotoxic Tumor Infiltrating Lymphocytes in Nasopharyngeal Carcinoma.- Generation of Cytotoxic T Cells Against EBV Infected B Lymphocytes.- T Cell Response to Peptides Encompassing a 5 Amino Acid Sequence Shared by the HLA DW4 DR Beta 1 Chain and the Epstein-Barr Virus Glycoprotein gp 110.- Growth Stimulation and Immunoglobulin (Ig) Secretion in Epstein-Barr Virus (EBV) Infected B Cells by Interleukin 6 (IL-6).- Presence of EBV Infected Cells in the Bone Marrow from Transplant Donors.- IV. Clinical Syndromes Associated with EBV Infections.- Clinical Syndromes Associated with Epstein-Barr Virus.- The Natural History and Treatment of EBV Infections and Their Nonmalignant Complications.- Epstein-Barr Virus Polymorphic Diffuse Lymphoma Associated with Leukemia and with Congenital Immunodeficiencies.- EB-Viral Expression Depends on the Differentiated Status of Epithelial Cells in Oral Hairy Leukoplakia.- EBV-Associated Lymphoproliferative Disorders in a Large Transplant Population.- EBV-Associated Head and Neck Tumours and Thymic Lesions.- Expression of EBV in the Nasopharyngeal Carcinoma-Derived Nude Mouse Tumour, C15.- Killer Cell Defect and Lack or Loss of Antibodies to Epstein-Barr Virus Glycoproteins in Chronic Active EBV.- Characterization of Cell Types and EBV Gene Expression in Lymphoproliferative Diseases (LPD) of Patients Receiving Bone Marrow Transplants (BMT) after T-Cell Depletion.- Epstein-Barr (EBV) Viral DNA in Tissues of Immunocompetent and Immunodeficient Children.- Different Cell Susceptibility to Epstein-Barr Virus Infection in a Patient with X-linked Lymphoproliferative Syndrome.- V. Diagnosis, Prevention, and Treatment of FSV-Associated Diseases.- Detection of EBV Specific IgA Antibodies to EA, MA, and EBNA-1 Recombinant Proteins in NPC Patients and Controls.- Challenges in the Treatment of EBV-Associated Diseases: New Approaches.- Epstein-Barr Virus Replication and Gene Expression in Oral "Hairy" Leukoplakia.- Changes in Virus-Host Genome Relationship in Two Sublines of the Same Burkitt's Lymphoma.- Molecular Weight Variation of EBNAs as a Means to Identify Different Epstein-Barr Virus Isolates (EBNotyping).- Cell-Mediated Responses to Epstein-Barr Virus Lytic Antigens.- Successful Therapy for EBV Associated B Cell Lymphoproliferative Disorders in Immunodeficiency Using Alpha Interferon and Intravenous Immunoglobulin.- Serological Correlation of HHV-6 and EBV Infections in Infectious Mononucleosis.- Natural Epstein-Barr Virus Isolates from Southern China and California Differ in the Bam H1I Region.- Antibodies Against EBNA-1 Derived Synthetic Peptide in Various Patient Groups.- Nasopharyngeal Carcinoma (NPC): The Influence of Different Types of Interferon (IFN) on Peripheral Blood Lymphocytes.- Early Diagnosis of Nasopharyngeal Carcinoma: A Multipronged Approach.- VI. Special Topics.- Cellular Receptors for Epstein-Barr Virus.- The Post-Infectious Chronic Fatigue Syndrome.- Post Viral Chronic Fatigue Syndrome: Persistence of Epstein-Barr Virus DNA in Muscle.- The Post-Infectious Chronic Fatigue Syndrome: Cell Surface Expression of LFA-1 and ICAM-1.- VII. Possible Cofactors in the Etiology of EB.- Epstein-Barr Virus (EBV)-Induced Transformation and EBV Genome Reorganization in Lymphoblastoid Cell Lines Established from Patients with AIDS Following Enhancement with Chemical Carcinogens.- Human Herpesvirus-6 (Human B Lymphotropic Virus).- Interactions of Epstein-Barr Virus with Human Retroviruses.- An Environmental Plant Factor Enhancing EBV-Specific Events in East Africa: Reduction of Killer T-Cell Function and Its Protection by Hot Spring Water.- Epstein-Barr Virus Antigens and Genome in Lymph Nodes from Patients with Persistent Generalized Lymphadenopathy (PGL).- Interaction of HBLV (HHV-6) with EBV and HIV.- Enhanced SV40 Immortalization of Primary Human Epidermal Cells Following Phorbol Ester Dependent EBV Transformation.- Food Extracts from High Risk Areas for NPC Induce an EBV Early Promoter.- List of Participant.
Series Title: Experimental biology and medicine (Clifton, N.J.)
Responsibility: edited by D.V. Ablashi [and others] ; technical editor, Kristinë L. Ablashi.

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...can be recommended as containing a wealth of source material, not otherwise easily accessible.-Reviews in Medical Virology

 
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