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Evolution-adjusted tumor pathophysiology : the novel language of tumor biology

Auteur : Albrecht Reichle
Éditeur: Dordrecht ; New York : Springer, ©2013.
Édition/format:   Livre électronique : Document : AnglaisVoir toutes les éditions et tous les formats
Résumé:
Combined modularized therapies for metastatic cancer are pointing to central problems of communication among 'systems participators'. A communication theory explains 'social engineering', endogenously induced or by implementing non-normative boundary conditions. Evolution-adjusted tumor pathophysiology is borne by an evolution theory, which contrasts narrative evolution histories. The tool of rationalizations  Lire la suite...
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Genre/forme: Electronic books
Format – détails additionnels: Printed edition:
Type d’ouvrage: Document, Ressource Internet
Type de document: Ressource Internet, Fichier d'ordinateur
Tous les auteurs / collaborateurs: Albrecht Reichle
ISBN: 9789400768666 9400768664
Numéro OCLC: 852664238
Notes: Includes index.
Description: 1 online resource
Contenu: Preface.-I Introduction.-Communication --
evolution --
pathophysiology: An endogenous conjunction --
Instead of an introduction.-II Combined modularized therapies for metastatic tumors: Pointing to central problems of communication among ' systems participators' in tumors --
Applied systems biology for the control of metastatic cancer: Therapeutic top-down strategy for targeting the tumors' normativity --
Targeting the proangiogenic network in angiosarcomas: Biomodulatory therapy.- Long-term results of combined modularized, immune-modulatory, angiostatic, and antiinflammatory therapy in systemically pre-treated multi-systems Langerhans cell histiocytosis.- Redirecting and modulating rationalizations of tumor-immanent normative functions in castration-resistant prostate ancer.-III Social engineering: Biomodulation, either endogenously initiated or by implementation of non-normative boundary conditions --
Non-hierarchically organized operations in malignancies: Stromal dysfunction induces hematopoetic malignancies.- Biomodulatory therapy approaches in renal clear cell carcinoma: A perspective.- Proteome analysis identified the PPARc ligand 15d-PGJ2 as a novel drug inhibiting melanoma progression and interfering with tumor-stroma interaction. IV The tumors' normativity: Reconstructing and operationalizing starting points for an evolution theory.- The philosophical quest of a cancer cell: Redefining existentialism.- The tumor' s normativity: Normative structures, action norms and decision maxims as therapeutic targets for tumor therapy.- Criticizable claims for the validity of communication acts in biological systems: Therapeutic implications in cancer.-V Evolution theory.- Evolution theory: Its practical relevance for understanding tumor development and specifying tumor therapy --
Modularity, subjectivity, intersubjectivity and normativity: Clinically applicable operative benchmarks --
Turning upside down the mode of science to emphasize and harness the impact of environmental communicative events. VI From genome- or organ-centric to rationalization-centric systematization of tumors --
Purposive-rational tumor therapy: Exploiting the tumor' s ' living world' for diversifying, specifying and personalizing tumor therapy --
Including rationalizations of tumor-associated normative notions in pathophysiologic considerations: Communication-theoretical implications.-VII Reconstruction of tumor-immanent normative functions, structures and decision maxims (hubs).- Bridging a diagnostic and therapeutic gap: Selecting, assessing and categorizing tumor-associated normative notions.- Personalizing tumor pathophysiology by diagnosing developmental problems in tumors with imaging techniques --
Biologic memory: Induction by metronomically administered combined modularized therapy.- VIII The tool of rationalizations constituting tumor-associated normative notions: The non-genomic counterpart of the tumor genome and therefore, an important therapeutic target for diversifying palliative care --
Diversifying and specifying palliative care for patients with metastatic cancer by therapeutic implementation of non-normative boundary conditions --
Targeting a hallmark of cancer: Simultaneous inflammation and tumor control for palliative care in metastatic cancer.-IX Novel clinical and pharmaceutical technology for bioengineering tumor response.- Combined modularized tumor therapy --
tumor biology --
and prognostic factors: Bioengineering tumor response.-X Objectifying the systems objects' subjectivity in biological systems: A novel reification of the scientific picture about the ' objective' world --
The systems objects' subjectivity as scientific object. Index. pt. I. Introduction --
pt. II. Combined modularized therapies for metastic tumors : pointing to central problems of communication among 'systems participators' in tumors --
pt. III. Social engineering : biomodulation, either endogenously initiated or by implementation of non-normative boundary conditions --
pt. IV. The tumors' normativity : reconstructing and operationalizing starting points for an evolution theory --
pt. V. Evolution theory --
pt. VI. From genome- or organ-centric to rationalization-centric systematization of tumors --
pt. VII. Reconstruction of tumor-immanent normative functions, structures and decision maxims (hubs) --
pt. VIII. The tool of rationalizations constituting tumor-associated normative notions : the non-genomic counterpart of the tumor genome and therefore, an important therapeutic target for diversifying palliative care --
pt. IX. Novel clinical and pharmaceutical technology for bioengineering tumor response --
pt. X. Objectifying the systems objects' subjectivity in biological systems : a novel reification of the scientific picture about the 'objective' world.
Responsabilité: Albrecht Reichle, editor.

Résumé:

This volume presents evolution-adjusted tumor pathophysiology, which allows implementing applied systems biology, a novel clinical and pharmaceutical technology for bioengineering tumor response and  Lire la suite...

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