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The evolution of vertebrate blood clotting

Author: Russell F Doolittle
Publisher: [Mill Valley, Calif.] : University Science Books, [2013] ©2013
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
"This book charts the step-by-step evolution of vertebrate blood coagulation. Intended for readers with a background in biological science, it is specifically targeted for those in the field of molecular evolution and researchers in the area of blood clotting. The orderly way in which gene duplications provided new genes for fine-tuning the system serves as a model for how complex physiological systems in general  Read more...
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Document Type: Book
All Authors / Contributors: Russell F Doolittle
ISBN: 9781891389818 1891389815
OCLC Number: 810082090
Description: xiii, 221 pages, 4 unnumbered pages of plates : illustrations (some color) ; 24 cm
Contents: Blood clotting in humans --
Clotting inhibitors and fibrinolysis --
Localizing clots --
Proteins and domains --
Fibrinogen and fibrin --
Animals, their proteins and phylogenetics --
Gene duplications --
Genomes --
Genomes of fish with jaws --
Lamprey clotting genes --
Contact factors and other embellishments --
Protochordate genomes --
Getting the system started.
Responsibility: Russell F. Doolittle.

Abstract:

After providing some general background in the areas of blood clotting, protein structure, animal systematics, and simple genomics, the book focusses in on the search for blood clotting genes in the  Read more...

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'Couldn't put it down! This book is simply wonderful. Although I already knew much of the science, it was explained in a way that helped me to put this work into the context of the larger narrative Read more...

 
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