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Excitatory amino acids : clinical results with antagonists

Author: P L Herrling
Publisher: San Diego : Academic Press, ©1997.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Glutamate is the major excitatory neurotransmitter in the brain and dysfunction of glutamate transmission is the likely cause of a variety of diseases including neurodegeneration following cerebral ischemia, Huntington's chorea, amyotrophic lateral sclerosis, epilepsy, spasticity, emesis, chronic pain, and schizophrenia. Excitatory amino acid receptor agonists and antagonists are therefore of major interest as  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Excitatory amino acids.
San Diego : Academic Press, ©1997
(OCoLC)36568957
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: P L Herrling
ISBN: 9780125468206 0125468202 9780080531342 0080531342
OCLC Number: 162128810
Reproduction Notes: Electronic reproduction. [S.l.] : HathiTrust Digital Library, 2010. MiAaHDL
Description: 1 online resource (xii, 156 pages) : illustrations
Details: Master and use copy. Digital master created according to Benchmark for Faithful Digital Reproductions of Monographs and Serials, Version 1. Digital Library Federation, December 2002.
Contents: M. Schmutz, A. Arthur, H. Faleck, G. Karlsson, A. Kotake, L. Landwicki, L. LaRue, S. Markabi, D. Murphy, M. Powell, and D. Sauer, Selfotel. --
P. Herrling et al., D-CPPene (SDZ EAA-494) A Competitive NMDA Antagonist: Pharmacology and Results in Humans. --
J.D. Kristensen, Intrathecal Administration of a Competitive NMDA Receptor Antagonist for Pain Treatment. --
A.G. Knapp, L.I. Matthews, and E.R. Gamzu, Clinical Experience with the NMDA Ion-Channel Blocker, Aptiganel Hydrochloride (CEROSTAT). --
M.-L. Maccecchini, Development of ACPC: A Partial Agonist of the Glycine Site on the NMDA Receptor. --
Carter et al., Ifenprodil and Eliprodil: Neuroprotective NMDA Receptor Antagonists and Calcium Channel Blockers. --
D. Lodge and D.D. Schoepp, 3S, 8aR-6-[2-(1(2)H-tetrazole-5-y)ethyl] Decahydroisoquinoline-3-carboxylic Acid (LY293558) and Its Racemate (LY215490): A Selective and Competitive AMPA/Kainate Receptor Agonist. --
L. Nordholm, M. Sheardown, and T. Honore, The NBQX Story. --
E. Louvel, Riluzole in Amytrophic Lateral Sclerosis. --
G.C. Plamer and J.B. Hutchinson, Preclinical and Clinical Aspects of Remacemide Hydrochloride.
Responsibility: edited by P.L. Herrling.

Abstract:

Presenting the results of human testing of modulators of excitatory amino acid neurotransmitters, this book provides coverage of the field of excitatory amino acids from synaptic function to  Read more...

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"This book is intended for research neuroscientists but can be effectively utilized by clinicians and students because of its clarity of style and excellent illustrations... Many excellent diagrams Read more...

 
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