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Fatty acids and lipotoxicity in obesity and diabetes.

Author: Gregory Bock; Jamie Goode; Novartis Foundation.; Qing hua da xue (Beijing, China)
Publisher: Chichester, UK ; Hoboken, NJ : John Wiley, 2007.
Series: Novartis Foundation symposium, 286.
Edition/Format:   Print book : Conference publication : EnglishView all editions and formats
Database:WorldCat
Summary:
The potential lipotoxic effect of accumulation of fatty acids in non-adipose tissues is thought to be a major component in the development of insulin resistance. Chronic exposure to high concentrations of free fatty acids in the blood affects pancreatic 'B' cell function, insulin secretion and lipid synthesis in the liver, and storage in adipose tissue. Maintaining the normal levels of fatty acids requires  Read more...
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Genre/Form: Congresses
Conference papers and proceedings
Congrès
Additional Physical Format: Online version:
Fatty acids and lipotoxicity in obesity and diabetes.
Chichester, UK ; Hoboken, NJ : John Wiley, 2007
(OCoLC)606382021
Online version:
Fatty acids and lipotoxicity in obesity and diabetes.
Chichester, UK ; Hoboken, NJ : John Wiley, 2007
(OCoLC)608607678
Material Type: Conference publication
Document Type: Book
All Authors / Contributors: Gregory Bock; Jamie Goode; Novartis Foundation.; Qing hua da xue (Beijing, China)
ISBN: 9780470057643 0470057645
OCLC Number: 190776533
Notes: Symposium on fatty acids and lipotoxicity in obesity and diabetes, held at Tsinghua University, Beijing, China, 17-19 Oct. 2006.
Editors: Gregory Bock and Jamie Goode.
Description: ix, 211 pages : illustrations.
Contents: Transcriptional control of energy homeostasis through the PGC1 coactivators / B.M. Spiegelman --
Human obesity and insulin resistance: lessons from experiments of nature / S. O'Rahilly --
Lipid-induced metabolic dysfunction in skeletal muscle / D.M. Muoio and T.R. Koves --
Stearoyl-CoA desaturase deficiency, hypercholesterolaemia, cholestasis and diabetes / A.D. Attie [and others] --
The role of lipin 1 in adipogenesis and lipid metabolism / K. Reue --
The role of the AMP-activated protein kinase in the regulation of energy homeostasis / D. Carling --
Endoplasmic reticulum stress and inflammation in obesity and type 2 diabetes / G.S. Hotamisligil --
The impact of insulin resistance on macrophage death pathways in advanced atherosclerosis / I. Tabas [and others] --
Fatty acid transport in adipocytes and the development of insulin resistance / S. Lobo and D.A. Bernlohr --
Vectorial acylation: linking fatty acid transport and activation to metabolic trafficking / P.N. Black and C.C. DiRusso --
Lipid storage and mobilization pathways in yeast / G. Daum [and others] --
Cide proteins and the development of obesity / J.Z. Li and P. Li --
Adiponectin and adiponectin receptors in obesity-linked insulin resistance / T. Kadowaki [and others] --
Anti-inflammatory and antidiabetic roles of PPARgamma / G. Pascual [and others].
Series Title: Novartis Foundation symposium, 286.

Abstract:

Fatty Acid and Lipotoxicity in Obesity and Diabetes deals with the molecular aspects of fatty acid action in obesity and insulin resistance. The topics include lipid metabolism and adipose tissue  Read more...

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