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Females are mosaics : X inactivation and sex differences in disease
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Females are mosaics : X inactivation and sex differences in disease

Author: Barbara R Migeon
Publisher: Oxford ; New York : Oxford University Press, 2007.
Edition/Format:   Book : EnglishView all editions and formats
Summary:

Talks about the X chromosome as a key to female development and the role of X-related factors in the etiology of sex differences in human disease. This book describes both the underlying molecular  Read more...

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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Barbara R Migeon
ISBN: 0195188128 9780195188127
OCLC Number: 65617406
Description: xi, 271 p., [8] p. of plates : ill. (some col.) ; 24 cm.
Contents: Introduction; PART I. BACKGROUND; 1. Sex Differences in Disease; 2. Evolution of the Human Sex Chromosomes and a Portrait of the Human X; 3. X Chromosome Dosage Compensation: An Overview; 4. The Discovery of X Chromosome Inactivation; 5. Experimental Models for X Inactivation Studies; PART II. THEMES AND VARIATIONS OF X INACTIVATION; 6. Theme 1: The Initial Steps - Creating the Active and Inactive X; 7. Theme 2: The Subsequent Steps - Spreading and Maintaining Inactivation; 8. Variations 1: Stability of the Inactive X; 9. Variations 2: Choice of Active X; PART III. MEDICAL CONSEQUENCES OF X INACTIVATION; 10. The Single Active X; 11. Mosaicism; 12. Determinants of Female Phenotypes
Other Titles: X inactivation and sex differences in disease
Responsibility: Barbara R. Migeon.
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