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Fluorescence lifetime spectroscopy and imaging : principles and applications in biomedical diagnostics

Author: Laura Marcu; Paul M W French; Daniel S Elson
Publisher: Boca Raton : CRC Press, [2015]
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
This book reflects the remarkable advances in time-resolved fluorescence techniques and their role in a wide range of biological and clinical applications. Fluorescence lifetime approaches maximize contrast between different fluorophores for improved specificity of measurements, enabling characterization of intact tissue and disease diagnostics. The book offers a comprehensive treatment of fundamental principles,  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Fluorescence lifetime spectroscopy and imaging.
Boca Raton : Taylor & Francis, 2014
(DLC) 2014002766
(OCoLC)666242805
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Laura Marcu; Paul M W French; Daniel S Elson
ISBN: 9781439861684 1439861684 1306866286 9781306866286
OCLC Number: 879945850
Description: 1 online resource (xv, 554 pages) : illustrations (some color)
Contents: Photophysics of fluorescence / Klaus Suhling --
Tissue fluorophores and their spectroscopic characteristics / Alzbeta Chorvatova and Dusan Chorvat --
Pulse sampling technique / Diego R. Yankelevich, Daniel S. Elson, and Laura Marcu --
Single point probes for lifetime spectroscopy : TCSPC technique / Christopher Dunsby and Paul M.W. French --
Optical instrumentation design for fluorescence lifetime spectroscopy and imaging / Peter T.C. So, Heejin Choi, Christopher J. Rowlands, and Vijay R. Singh --
Fluorescence lifetime imaging techniques : frequency-domain FLIM / John P. Eichorst, Kai wen Teng, and Robert M. Clegg --
Fluorescence lifetime imaging techniques : time-gated FLIM / James McGinty, Christopher Dunsby, and Paul M.W. French --
Fluorescence lifetime imaging techniques : TCSPC / Wolfgang Becker --
The phasor approach to FLIM : exploiting phasor linear properties / Michelle A. Digman and Enrico Gratton --
Analysis of time domain fluorescence measurements using least-squares deconvolution / Jing Liu, Daniel S. Elson, and Laura Marcu --
Global analysis of FLIM-FRET data / Hernán E. Grecco and Peter J. Verveer --
Fluorescence lifetime imaging in turbid media / Vadim Y. Soloviev, Teresa M. Correia, and Simon R. Arridge --
Oncology applications : optical diagnostics of cancer / Alzbeta Chorvatova and Dusan Chorvat --
Oncological applications : brain / Pramod V. Butte, Adam N. Mamelak, and Laura Marcu --
Oncology applications : skin cancer / Rakesh Patalay, Paul M.W. French, and Christopher Dunsby --
Oncology applications : gastrointestinal cancer / Sergio Coda, Paul M.W. French, and Christopher Dunsby --
Oncology applications : intraoperative diagnosis of head and neck carcinoma / D. Gregory Farwell --
Fluorescence lifetime techniques in cardiovascular disease diagnostics / Jennifer Phipps, Yang Sun, and Laura Marcu --
Ophthalmic applications of FLIM / Dietrich Schweitzer --
Fluorescence lifetime imaging applications in tissue engineering / Bernard Y. Binder, J. Kent Leach, and Laura Marcu --
Tomographic fluorescence lifetime imaging / Anand T.N. Kumar --
Photosensitizers and PDT / Rinaldo Cubeddu, Paola Taroni, and Gianluca Valentini --
Fluorescence lifetime imaging of ions in biological tissues / Christoph Biskup and Thomas Gensch.
Responsibility: edited by Laura Marcu, Paul M.W. French, Daniel S. Elson.

Abstract:

This book reflects the remarkable advances in time-resolved fluorescence techniques and their role in a wide range of biological and clinical applications. Fluorescence lifetime approaches maximize contrast between different fluorophores for improved specificity of measurements, enabling characterization of intact tissue and disease diagnostics. The book offers a comprehensive treatment of fundamental principles, instrumentation, analytical methods, and applications. It covers the wide range of methods, including single channel (point) spectroscopy, fluorescence lifetime imaging microscopy, and single- and multi-photon excitation.

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"This highly recommended comprehensive volume is a good resource for investigators who wish to apply these techniques. It is a self-contained book in which the physics and the analytical methods are Read more...

 
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