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Fluorine in pharmaceutical and medicinal chemistry : from biophysical aspects to clinical applications

Author: Véronique Gouverneur; Klaus Müller, (Pharmacist)
Publisher: London : Imperial College Press ; Hackensack, NJ : Distributed by World Scientific, ©2012.
Series: Molecular medicine and medicinal chemistry, v. 6.
Edition/Format:   Book : EnglishView all editions and formats
Database:WorldCat
Summary:

Fluorine chemistry is an expanding area of research that is attracting international interest, due to the impact of fluorine in drug discovery and in clinical and molecular imaging. This book  Read more...

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Document Type: Book
All Authors / Contributors: Véronique Gouverneur; Klaus Müller, (Pharmacist)
ISBN: 9781848166349 1848166346
OCLC Number: 801027663
Description: xxiii, 546 p. : ill. (some col.) ; 24 cm.
Contents: Molecular Interactions of Fluorinated Amino Acids within the Hydrophobic Core of a Coiled Peptide; Synthesis and Properties of Fluorinated Nucleobases in DNA and RNA; Fluorine-18 Labelled Tracers for PET Oncology and Neurology Applications; Synthesis of Fluorinated Neurotransmitter Analogues; 19F NMR: Clinical and Molecular Imaging Applications; Strategic Incorporation of Fluorine into Taxoids Anticancer Agents; Synthesis and Antiviral, Antitumor Activities of Fluorinated Sugar Nucleosides; Trifluoromethyl-substituted α-Amino Acids as Solid State 19F-NMR Labels for Structural Studies of Membrane-Bound Peptides; Applications of Pentafluorosulfanyl Substitution in Life Sciences Research; Probing the Binding Affinity and Proteolytic Stability of Trifluoromethyl Peptide Mimics as Protease Inhibitors.
Series Title: Molecular medicine and medicinal chemistry, v. 6.
Responsibility: Véronique Gouverneur, Klaus Müller, editors.

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