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From molecules to medicines : structure of biological macromolecules and its relevance in combating new diseases and bioterrorism

Author: Joel Sussman; Paola Spadon
Publisher: Dordrecht : Springer : In cooperation with NATO Public Diplomacy Division, ©2009.
Series: NATO science for peace and security series., Series A,, Chemistry and biology
Edition/Format:   Print book : Conference publication : EnglishView all editions and formats
Summary:

Proceedings of the NATO Advanced Study Institute on Integrating Crystallography in the Fight Against TerrorismErice, Italy29 May-8 June 2008

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Genre/Form: Congresses
Conference papers and proceedings
Material Type: Conference publication
Document Type: Book
All Authors / Contributors: Joel Sussman; Paola Spadon
ISBN: 9789048123377 9048123372 9789048123384 9048123380 9789048123391 9048123399
OCLC Number: 373548337
Description: xv, 251 pages : illustrations ; 24 cm.
Contents: Surface proteins of gram-positive pathogens : using crystallography to uncover novel features in drug and vaccine candidates / Edward N. Baker, Thomas Proft, Haejoo Kang --
The rapid crystallization strategy for structure-based inhibitor design / Terese Bergfors --
Fragment-based drug discovery in academia : experiences from a tuberculosis programme / Timo J. Heikkila, Sachin Surade, Hernani L. Silvestre [and others] --
Structural biology contributions to the discovery of drugs to treat chronic myelogenous leukemia / Sandra W. Cowan-Jacob, Gabriele Fendrich, Andreas Floersheimer [and others] --
Integrating crystallography into early metabolism studies / Gabriele Cruciani, Yasmin Aristei, Laura Goracci [and others] --
The foundations of protein-ligand interaction / Gerhard Klebe --
Structure-based design of TRNA-Guanine transglycosylase inhibitors / Gerhard Klebe --
Progress on new hepatitis C virus targets : NS2 and NS5A / Joseph Marcotrigiano --
Protein structure modeling / Narayanan Eswar, Andrej Sali --
Structural biology and molecular modeling in the design of novel DPP-4 inhibitors / Giovanna Scapin --
Tools to make 3D structural data more comprehensible : emovie & proteopedia / Eran Hodis, Jaime Prilusky, Joel L. Sussman --
Structural studies on acetylcholinesterase and paraoxonase directed towards development of therapeutic biomolecules for the treatment of degenerative diseases and protection against chemical threat agents / Joel L. Sussman, Israel Silman --
Protein function prediction from structure in structural genomics and its contribution to the study of health and disease / James D. Watson, Janet M. Thornton --
Crystal structures of the ß₂-adrenergic receptor / William I. Weis, Daniel M. Rosenbaum, Søren G.F. Rasmussen [and others] --
Can structures lead to better drugs? Lessons from ribosome research / Ada Yonath.
Series Title: NATO science for peace and security series., Series A,, Chemistry and biology
Responsibility: edited by Joel L. Sussman and Paola Spadon.

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