skip to content
Fundamentals of chromatin Preview this item
ClosePreview this item
Checking...

Fundamentals of chromatin

Author: Jerry L Workman; Susan M Abmayr
Publisher: New York : Springer Science+Business Media, [2014] ©2014
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
While there has been an increasing number of books on various aspects of epigenetics, there has been a gap over the years in books that provide a comprehensive understanding of the fundamentals of chromatin.?Chromatin is the combination of DNA and proteins that make up the genetic material of chromosomes. Its primary function is to package DNA to fit into the cell, to strengthen the DNA to prevent damage, to allow  Read more...
Rating:

(not yet rated) 0 with reviews - Be the first.

Subjects
More like this

Find a copy online

Links to this item

Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...

Details

Genre/Form: Electronic books
Additional Physical Format: Print version:
Workman, Jerry L.
Fundamentals of Chromatin.
Dordrecht : Springer, ©2013
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Jerry L Workman; Susan M Abmayr
ISBN: 9781461486244 1461486246 1461486238 9781461486237
OCLC Number: 868922748
Description: 1 online resource (594 pages) : illustrations
Contents: Preface; Contents; Contributors; Chapter 1: Histone, Nucleosome, and Chromatin Structure; 1.1 Introduction to Chromatin Structure; 1.2 A History of Chromatin Structure; 1.3 The Nucleosome Core Particle Structure; 1.3.1 Overview of the High-Resolution Nucleosome Core Particle Structure; 1.3.2 Primary Structure of Histones; 1.3.3 Secondary Structure of Core Histones and the Architecture of the Histone Octamer; 1.3.4 Core Histone Tails and Extensions; 1.3.5 The DNA Superhelix and Core Histone-DNA Interactions; 1.3.6 The Nucleosome Core Particle Surface and Interactions. 1.3.7 Nucleosome Core Dynamics: PTMs, Variants, DNA Breathing, and Suboctameric Particles1.4 Linker Histone and the Chromatosome; 1.5 Higher-Order Chromatin Structure; 1.5.1 Secondary Structure of Chromatin; 1.6 Perspective; References; Chapter 2: Histone Chaperones in the Assembly and Disassembly of Chromatin; 2.1 Introduction; 2.1.1 A Working Model for Stepwise Nucleosome Assembly/Disassembly; 2.1.2 Overview of Histone Chaperones; 2.2 Histone Transport from the Cytoplasm to the Nucleus; 2.3 Replication-Dependent Chromatin Assembly; 2.3.1 Histone Eviction in Front of the Replication Fork. 2.3.2 Histone Deposition Behind the Replication Fork2.3.2.1 H3-H4 Deposition onto Newly Replicated DNA; 2.3.2.2 H2A-H2B and H1 Deposition onto Newly Replicated DNA; 2.3.2.3 Reassembly of Heterochromatin; 2.4 Reassembly of Centromeric Chromatin; 2.4.1 CenH3 Chaperones and Their Function; 2.5 Histone Chaperones in Replication-Independent Chromatin Disassembly and Assembly; 2.5.1 (H3-H4) 2 Tetramer Splitting; 2.5.2 Exchange of H2A.Z; 2.5.3 Exchange of H3.3; 2.5.4 Transcription-Dependent Chromatin Disassembly and Reassembly; 2.5.4.1 Asf1; 2.5.4.2 FACT; 2.5.4.3 Spt6. 2.6 Histone Chaperones in Chromatin Assembly and Disassembly During DNA Repair2.7 Concluding Remarks; References; Chapter 3: Chromatin Remodeling Complexes; 3.1 Introduction; 3.1.1 Composition and Biophysical Properties of Nucleosomes; 3.1.2 Concepts of Nucleosome Phasing and Spacing; 3.2 Classification of Remodelers; 3.2.1 Chromatin Processes and Remodeler Functions; 3.2.1.1 Chromatin Deposition and Assembly; 3.2.1.2 Chromatin Editing; 3.2.1.3 Chromatin Access; 3.2.2 Compositional Attributes Shared by Remodelers; 3.2.3 Remodeler Families and Compositional Specialization; 3.2.3.1 ISWI Family. 3.2.3.2 CHD Family3.2.3.3 INO80 Family; 3.2.3.4 SWI/SNF Family; 3.2.3.5 "Orphan" Remodelers; 3.2.4 PTM-Interacting Motifs and Combinatorial Regulation; 3.2.4.1 Bromodomain; 3.2.4.2 BAH Domain; 3.2.4.3 CHD Domain; 3.2.4.4 PHD Domain; 3.2.5 Remodeler Motif Utilization; 3.3 Remodeler Mechanisms and Regulation; 3.3.1 DNA Translocation Underlies Remodeler Mechanisms and Outcomes; 3.3.2 Mechanisms and Regulation of Chromatin Access; 3.3.3 Mechanisms and Regulation of Chromatin Assembly; 3.3.4 Mechanisms and Regulation of Chromatin Editing Involving H2A Variants.
Responsibility: Jerry L. Workman, Susan M. Abmayr, editors.

Abstract:

This book focuses on fundamental properties of chromatin that include structure, composition, modifications and functions in nuclear processes such as transcription, and DNA replication and repair.  Read more...

Reviews

User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

Be the first.
Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Linked Data


Primary Entity

<http://www.worldcat.org/oclc/868922748> # Fundamentals of chromatin
    a schema:CreativeWork, schema:MediaObject, schema:Book ;
    library:oclcnum "868922748" ;
    library:placeOfPublication <http://id.loc.gov/vocabulary/countries/nyu> ;
    schema:about <http://dewey.info/class/572.87/e23/> ;
    schema:about <http://experiment.worldcat.org/entity/work/data/1748775718#Topic/chromatin_physiology> ; # Chromatin--physiology
    schema:about <http://experiment.worldcat.org/entity/work/data/1748775718#Topic/science_life_sciences_biochemistry> ; # SCIENCE--Life Sciences--Biochemistry
    schema:about <http://experiment.worldcat.org/entity/work/data/1748775718#Topic/chromatin> ; # Chromatin
    schema:about <http://experiment.worldcat.org/entity/work/data/1748775718#Topic/epigenetics> ; # Epigenetics
    schema:bookFormat schema:EBook ;
    schema:contributor <http://viaf.org/viaf/23073466> ; # Jerry L. Workman
    schema:contributor <http://viaf.org/viaf/309829463> ; # Susan M. Abmayr
    schema:copyrightYear "2014" ;
    schema:datePublished "2014" ;
    schema:description "Preface; Contents; Contributors; Chapter 1: Histone, Nucleosome, and Chromatin Structure; 1.1 Introduction to Chromatin Structure; 1.2 A History of Chromatin Structure; 1.3 The Nucleosome Core Particle Structure; 1.3.1 Overview of the High-Resolution Nucleosome Core Particle Structure; 1.3.2 Primary Structure of Histones; 1.3.3 Secondary Structure of Core Histones and the Architecture of the Histone Octamer; 1.3.4 Core Histone Tails and Extensions; 1.3.5 The DNA Superhelix and Core Histone-DNA Interactions; 1.3.6 The Nucleosome Core Particle Surface and Interactions."@en ;
    schema:description "While there has been an increasing number of books on various aspects of epigenetics, there has been a gap over the years in books that provide a comprehensive understanding of the fundamentals of chromatin.?Chromatin is the combination of DNA and proteins that make up the genetic material of chromosomes. Its primary function is to package DNA to fit into the cell, to strengthen the DNA to prevent damage, to allow mitosis and meiosis, and to control the expression of genes and DNA replication. The audience for this book is mainly newly established scientists?and graduate studen."@en ;
    schema:exampleOfWork <http://worldcat.org/entity/work/id/1748775718> ;
    schema:genre "Electronic books"@en ;
    schema:inLanguage "en" ;
    schema:isSimilarTo <http://worldcat.org/entity/work/data/1748775718#CreativeWork/fundamentals_of_chromatin> ;
    schema:name "Fundamentals of chromatin"@en ;
    schema:productID "868922748" ;
    schema:url <http://proxy.library.carleton.ca/login?url=http://dx.doi.org/10.1007/978-1-4614-8624-4> ;
    schema:url <http://dx.doi.org/10.1007/978-1-4614-8624-4> ;
    schema:url <http://link.springer.com/10.1007/978-1-4614-8624-4> ;
    schema:url <http://public.eblib.com/choice/publicfullrecord.aspx?p=1592901> ;
    schema:url <https://link.springer.com/openurl?genre=book&isbn=978-1-4614-8623-7> ;
    schema:url <http://site.ebrary.com/id/10815177> ;
    schema:url <http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=671718> ;
    schema:url <http://link.springer.com/openurl?genre=book&isbn=978-1-4614-8623-7> ;
    schema:url <http://proxy.library.carleton.ca/login?url=http://books.scholarsportal.info/viewdoc.html?id=/ebooks/ebooks3/springer/2014-04-01/1/9781461486244> ;
    schema:url <https://grinnell.idm.oclc.org/login?url=http://link.springer.com/10.1007/978-1-4614-8624-4> ;
    schema:workExample <http://worldcat.org/isbn/9781461486244> ;
    schema:workExample <http://dx.doi.org/10.1007/978-1-4614-8624-4> ;
    schema:workExample <http://worldcat.org/isbn/9781461486237> ;
    wdrs:describedby <http://www.worldcat.org/title/-/oclc/868922748> ;
    .


Related Entities

<http://experiment.worldcat.org/entity/work/data/1748775718#Topic/chromatin_physiology> # Chromatin--physiology
    a schema:Intangible ;
    schema:name "Chromatin--physiology"@en ;
    .

<http://experiment.worldcat.org/entity/work/data/1748775718#Topic/science_life_sciences_biochemistry> # SCIENCE--Life Sciences--Biochemistry
    a schema:Intangible ;
    schema:name "SCIENCE--Life Sciences--Biochemistry"@en ;
    .

<http://viaf.org/viaf/23073466> # Jerry L. Workman
    a schema:Person ;
    schema:familyName "Workman" ;
    schema:givenName "Jerry L." ;
    schema:name "Jerry L. Workman" ;
    .

<http://viaf.org/viaf/309829463> # Susan M. Abmayr
    a schema:Person ;
    schema:familyName "Abmayr" ;
    schema:givenName "Susan M." ;
    schema:name "Susan M. Abmayr" ;
    .

<http://worldcat.org/entity/work/data/1748775718#CreativeWork/fundamentals_of_chromatin>
    a schema:CreativeWork ;
    rdfs:label "Fundamentals of Chromatin." ;
    schema:description "Print version:" ;
    schema:isSimilarTo <http://www.worldcat.org/oclc/868922748> ; # Fundamentals of chromatin
    .

<http://worldcat.org/isbn/9781461486237>
    a schema:ProductModel ;
    schema:isbn "1461486238" ;
    schema:isbn "9781461486237" ;
    .

<http://worldcat.org/isbn/9781461486244>
    a schema:ProductModel ;
    schema:isbn "1461486246" ;
    schema:isbn "9781461486244" ;
    .


Content-negotiable representations

Close Window

Please sign in to WorldCat 

Don't have an account? You can easily create a free account.