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G protein coupled receptors : structure

Author: P Michael Conn
Publisher: San Diego, Calif. : Academic Press/Elsevier, 2013. ©2013
Series: Methods in enzymology, v. 520.
Edition/Format:   Print book : English : First editionView all editions and formats

Covers G protein coupled receptors and includes chapters on topics such as post-translation modification of GPCR in relationship to biased agonism, structure-based virtual screening, and GPCR  Read more...


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Document Type: Book
All Authors / Contributors: P Michael Conn
ISBN: 0123918618 9780123918611
OCLC Number: 813210742
Description: liv, 384 pages, 12 unnumbered pages of plates : illustrations (some color) ; 24 cm.
Contents: Expression of GPCRs in Pichia pastoris for structural studies / Christoph Krettler, Christoph Reinhart, and Carville G. Bevans --
Conformational ensemble view of G protein-coupled receptors and the effect of mutations and ligand binding / Ravinder Abrol, Soo-Kyung Kim, Jenelle K. Bray, Bartosz Trzaskowski, and William A. Goddard, III --
Structural evolution of G-protein-coupled receptors : a sequence space approach / Jean Michel Bécu, Julien Pelé, Patrice Rodien, Hervé Abdi, and Marie Chabbert --
Directed evolution of G-protein-coupled receptors for high functional expression and detergent stability / Karola M. Schlinkmann and Andreas Plückthun --
The role of hydrophobic amino acids in the structure and function of the Rhodopsin family of G protein-coupled receptors / Gianluigi Caltabiano, Angel Gonzalez, Arnau Cordomí, Mercedes Campillo, and Leonardo Pardo --
Structure of [beta]-adrenergic receptors / Florian Brueckner, Chayne L. Piscitelli, Ching-Ju Tsai, Jörg Standfuss, Xavier Deupi, and Gebhard F.X. Scherler --
Advances in methods to characterize ligand-induced ionic lock and rotamer toggle molecular switch in G protein-coupled receptors / Xiang-Qun Xie and Ananda Chowdhury --
Crystallogenesis of adenosine A[subscript 2A] receptor-T4 lysozyme fusion protein : a practical route for the structure / Yashwanth Ashok, Rahul T. Nanekar, and Veli-Pekka Jaakola --
Probing GPCR structure : adenosine and P2Y nucleotide receptors / Kenneth A. Jacobson, Stefano Costanzi, and Francesca Deflorian --
Strategies for studying the ligand binding site of GPCRs : photoaffinity labeling of the VPAC1 receptor, a prototype of Class B GPCRs / Alain Couvineau, Yossan-Var Tan, Emile Ceraudo, and Marc Laburthe --
Expression of mammalian G protein-coupled receptors in Caenorhabditis elegans / Beata Jastrzebska, David Salom, Hui Jin, Pengxiu Cao, Wenyu Sun, Krzysztof Palczewski, and Zhaoyang Feng --
Expression, purification, and structural analysis of intracellular C-termini from metabotropic glutamate receptors / Angela Seebahn, Heinrich Sticht, and Ralf Enz --
Unnatural amino acid mutagenesis of GPCRs using amber codon suppression and bioorthogonal labeling / Thomas Huber, Saranga Naganathan, He Tian, Shixin Ye, and Thomas P. Sakmar --
Mapping a ligand binding site using genetically encoded photoactivatable crosslinkers / Amy Grunbeck, Thomas Huber, and Thomas P. Sakmar --
Alternative mRNA splicing of G protein-coupled receptors / Danijela Markovic --
Functional residues essential for the activation of the CB1 cannabinoid receptor / Joong-Youn Shim and Lea Padgett.
Series Title: Methods in enzymology, v. 520.
Responsibility: edited by P. Michael Conn.


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