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GAPDH : biological properties and diversity

Author: Norbert W Seidler
Publisher: Dordrecht ; New York : Springer, ©2013.
Series: Advances in experimental medicine and biology, 985.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
GAPDH (glyceraldehyde 3-phosphate dehydrogenase) is more than just a glycolytic enzyme. An unprecedented amount of literature demonstrates that GAPDH has an astounding multiplicity of function. This diversity is not simply due to cell compartmentation (i.e. redistributing glycolytic energy to where it is needed), although this feature is undoubtedly important and discussed in the book. GAPDH integrates glycolysis  Read more...
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Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Norbert W Seidler
ISBN: 9789400747166 9400747160
OCLC Number: 806230389
Description: 1 online resource.
Contents: Basic Biology of GAPDH --
GAPDH and Intermediary Metabolism --
Compartmentation of GAPDH --
Functional Diversity --
GAPDH, as a Virulence Factor --
Target for Diverse Chemical Modifications --
Dynamic Oligomeric Properties --
Multiple Binding Partners --
GAPDH in Anesthesia.
Series Title: Advances in experimental medicine and biology, 985.
Responsibility: Norbert W. Seidler.
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Abstract:

Presents a review and synthesis of the biomedical literature that spans over a half-century on a single protein called glyceraldehyde 3-phosphate dehydrogenase (or, GAPDH). Suitable for the  Read more...

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From the book reviews: "The biochemical, physiological, and metabolic roles of GAPDH is discussed starting with the cell membrane and ionic mechanisms of glycolysis, energetics, and the TCA cycle. Read more...

 
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