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Gene Transfer and the Ethics of First-in-Human Research : Lost in Translation.

Author: Jonathan Kimmelman
Publisher: Leiden : Cambridge University Press, 2009.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Examines the ethical and policy dimensions of testing novel medical interventions in human beings for the first time.
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Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Jonathan Kimmelman
ISBN: 9780511640490 0511640498
OCLC Number: 609846212
Description: 1 online resource (219 pages)
Contents: Cover; Half-title; Title; Copyright; Dedication; Contents; Acknowledgments; Abbreviations; Chapter 1 Introduction: gene transfer lost in translation; Chapter 2 What is gene transfer?; Chapter 3 Safety, values, and legitimacy: the protean nature of risk in translational trials; Chapter 4 Taming uncertainty: risk and gene-transfer clinical research; Chapter 5 Succor or suckers? Benefit, risk, and the therapeutic misconception; Chapter 6 Looking backward: a model of value for translational trials; Chapter 7 The chasm: the ethics of initiating first-in-human clinical trials. Chapter 8 Tropic of cancers: gene transfer in resource-poor settingsChapter 9 Great Expectations and Hard Times: expectation management in gene transfer; Chapter 10 Something in the sight adjusts itself: conclusions; Epilogue; Index.

Abstract:

Examines the ethical and policy dimensions of testing novel medical interventions in human beings for the first time.  Read more...

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