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Genetic instability and tumorigenesis

Author: M B Kastan
Publisher: Berlin ; New York : Springer, ©1997.
Series: Current topics in microbiology and immunology, 221.
Edition/Format:   Print book : EnglishView all editions and formats
Database:WorldCat
Summary:
This book reviews our current level of understanding of the role of genetic instability in human tumorgenesis. In this incredibly rapidly moving field, discoveries in recent years have elucidated a number of important gene products which control cellular responses to DNA damaging agents, such as DNA repair and cell cycle perturbations. Mutations in these genes appear to be important contributors to the development
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Genre/Form: Aufsatzsammlung
Document Type: Book
All Authors / Contributors: M B Kastan
ISBN: 9783540615187 3540615180
OCLC Number: 36076778
Description: 180 pages : illustrations.
Contents: Genetic Instability and Tumorigenesis: Introduction / M.B. Kastan --
Genomic Stability and Instability: A Working Paradigm / K.C. Cheng and L.A. Loeb --
Surveillance and Genome Stability in Budding Yeast: Implications for Mammalian Carcinogenesis / F. Spencer --
Genomic Instability and Its Roles in Neoplasia / T.D. Tlsty --
Role of DNA Excision Repair Gene Defects in the Etiology of Cancer / J.M. Ford and P.C. Hanawalt --
Chromosome Instability Syndromes: Lessons for Carcinogenesis / M.S. Meyn --
Genetic Alterations in Human Tumors / K.R. Cho and L. Hedrick.
Series Title: Current topics in microbiology and immunology, 221.
Responsibility: edited by M.B. Kastan.
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This volume reviews the level of understanding of the role of genetic instability in human tumourigenesis. It covers a range of topics from scientific insights into genetic instability learned from  Read more...

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