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Genetics of Immunological Diseases

Author: Beverly Mock; Michael Potter
Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 1988.
Series: Current topics in microbiology and immunology, 137.
Edition/Format:   eBook : Document : EnglishView all editions and formats
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Beverly Mock; Michael Potter
ISBN: 9783642500596 3642500595
OCLC Number: 851823601
Description: 1 online resource (xi, 335 pages 88 illustrations).
Contents: I. Localizing and Cloning Genes.- The Long-Range Mapping of Mammalian Chromosomes.- The Use of Interspecific Mouse Crosses for Gene Localization: Present Status and Future Perspectives.- X-Chromosome Gene Order in Different Mus Species Crosses.- Bayesian Multilocus Linkage Mapping.- The Rat Gene Map.- Linkage and Synteny Homologies in Mouse and Man.- Molecular Analysis of the Aniridia - Wilms' Tumor Syndrome.- Approaching the Mouse Steel Locus from Closely Linked Molecular Markers.- II. Complex Loci Involved in the Regulation of Developmental and Immunological Processes.- The Mouse t Complex.- Probing Mouse Origins with Random DNA Probes.- Mouse t Haplotypes: A Tale of Tails and a Misunderstood Selfish Chromosome.- Contrasting Patterns of Evolution in the Proximal and Distal Regions of the Mouse t Complex.- From Phenotype to Gene: Molecular Cloning in the Brachyury (T) Locus Region.- Mouse Homeo Box Genes.- Murine Hox Genes - A Multigene Family.- Expression of the Homeobox Genes Hox 2.1 and 2.6 During Mouse Development.- Immunoglobulin Superfamily Genes.- Studies of V(D)J Recombination with Extrachromosomal Substrates.- Transcription Factors in Terminally Differentiated B Cells.- Selective and Neutral Evolution in the Murine Igh-V Locus.- The Organization of the Immunoglobulin Kappa Locus in Mice.- Conservation of the Organization of the pre-B Cell Specific VpreB1/VpreB2/?5 Loci in the Genus Mus.- The Omega and Iota Surrogate Immunoglobulin Light Chains.- MHC Class I Gene Expression by Tumors: Immunotherapeutic Implications.- Identification of Regulatory Elements Associated with a Class I MHC Gene.- Tind, Tsu and Tthy form a Trimolecular Complex Encoded Within the Tsu Locus on Chromosome 12 of the Mouse.- III. Allelomorphic and Mutant Phenotypes.- Immunologically Related Loc.- Lps Gene-Associated Functions.- The Immunobiology of the T Cell Response to Mls Locus Disparate Stimulator Cells.- Genetic Analysis of Serologically Undefined Determinants: A T Cell "Clonological" Analysis of the Mls System.- X-Chromosome Linked Mutations Affecting Mosaic Expression of the Mouse X Chromosome.- Mosaic Analysis of the Effects of a Novel X-Chromosome Mutation on the Haematopoietic System.- Autoimmunity.- The scid Mouse Mutant.- Aberrant Igh Locus Rearrangements in A-MuLV pre B Lines of scid Mice: Evidence for Deregulated D-J Recombination.- VH Family Usage and Binding Analyses of Polyreactive Monoclonal Autoantibodies Derived from Nonimmunized Adult BALB/c Mice.- Pleiotropic Effects of Deleterious Alleles at the "Motheaten" Locus.- Characterization of Mott Cell Hybridomas from Autoimmune "Viable Motheaten" Mutant Mice.- A Molecular Genetic Approach to gld "Autoimmune" Disease.- Genetic Analysis of BALB/cJ Subline Resistance to Actively Induced Experimental Allergic Orchitis (EAO) and Experimental Allergic Encephalomyelitis (EAE).- Neoplasia.- Genetic Control of Murine Susceptibility to 3-Methylcholanthrene-Induced T Cell Lymphoma.- Multigenic Control of Colon Carcinogenesis in Mice Treated with 1,2-Dimethylhydrazine.- Effect of the Gv-1 Locus on Moloney Ecotropic Murine Leukemia Virus Induced Disease in Inbred and Wild Mice.- Reverse Genetics Approaches for Cloning RIL-1, a Major Locus Involved in Susceptibility to Leukemia.- Genetic Map Location of Afr-1: Results From Four Genetic Crosses.- The Effect of the nude Gene on Plasmacytoma Development in BALB/cAn Mice.- Organization of the Distal End of Mouse Chromosome 4.- Susceptibility and Resistance to Plasmacytomagenesis: Possible Role of Genes That Modify Efficiency of Chromatin Repair.- A Molecular Characterization of BALB/c Congenie C.D2-Idh-1b, Lshr, Rep-1b, Pep-3bMice.- Infectious Diseases.- Analysis of Lsh Gene Expression in Congenic B10.L-Lshr Mice.- Identification of a Linkage Group Including the Bcg Gene by Restriction Fragment Length Polymorphism Analysis.- Continuous Expression of I-A by Murine Peritoneal Macrophages IS Linked to the Bcg Gene.- Chromosomal Location of the Gene Determining Restistance to Plasmodium chabaudi AS.- Summary.- From Phenotype to Gene: A Molecular Analysis of Complex Loci Involved in Developmental and Immunological Dysregulation.- Indexed in Current Contents.
Series Title: Current topics in microbiology and immunology, 137.
Responsibility: edited by Beverly Mock, Michael Potter.
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