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Genome-wide association studies : from polymorphism to personalized medicine

Author: Krishnarao Appasani
Publisher: Cambridge : Cambridge University Press, 2016.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

Experts from academia and industry highlight the potential of genome-wide association studies from basic science to clinical and biotechnological/pharmaceutical applications.

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Document Type: Book
All Authors / Contributors: Krishnarao Appasani
ISBN: 9781107042766 1107042763
OCLC Number: 913072811
Description: xxxi, 391 pages : illustrations ; 26 cm
Contents: Introduction to genome wide association / Krishnarao Appasani and Raghu K. Appasani --
GWAS : a milestone in the road from genotypes to phenotypes / Urko Martinez-Marigorta, Juan Antonio Rodriguez, and Arcadi Navarro --
Introduction to statistical methods in genome-wide association studies / Can Yang, Cong Li, Dongjun Chung, Mengjie Chen, Joel Gelernter, and Hongyu Zhao --
GWAS replicability across time and space / Urko Martinez-Marigorta, Juan Antonio Rodriguez, and Arcadi Navarro --
Genome-wide association studies of body mass index / Tuomas O. Kilpelainen --
Identification of myocardial infarction susceptible genes and their functional analyses / Kouichi Ozaki and Toshihiro Tanaka --
Admixture mapping for disease gene discovery / Randall C. Johnson, Cheryl A. Winkler, and Meredith Yeager --
Genome-wide association analysis in schizophrenia / Sven Stringer, Dorien H. Nieman, Rene S. Kahn, and Eske M. Derks --
Epigenome-wide association studies in neurodevelopmental disorders / Takeo Kubota, Kunio Miyake, and Takae Hirasawa --
Finding SNPs that affect microRNA regulation in disease-associated genomic regions / Laurent F. Thomas and Pal Saetrom --
From linkage to complex associations : the role of GABRA2 as a risk factor for alcohol use / Sandra Villafuerte, Elisa M. Trucco, and Margit Burmeister --
Copy number variation in monozygous twins / Erwin Brosens, K.G. Snoek, D. Veenma, H. Eussen, D. Tibboel, and A. de Klein. Haplotypes of CpG-related SNPs and association with DNA methylation patterns / Yiyi Ma, Caren E. Smith, Yu-Chi Lee, Laurence D. Parnell, Chao-Qiang Lai, and Jose M. Ordovas --
eQTL mapping / Mengjie Chen, Can Yang, Cong Li, and Hongyu Zhao --
Next-generation sequencing for rare diseases / Elena Bosch and Ferran Casals --
Next-generation sequencing for complex disorders / Ferran Casals and Elena Bosch --
Chromosomal breakpoints in breast cancer co-localize with differentially methylated regions / Man-Hung Eric Tang, Vinay Varadan, Sitharthan Kamalakaran, Michael Q. Zhang, James Hicks, and Nevenka Dimitrova --
Signaling network analysis of genomic alterations predict breast cancer drug targets / Naif Zaman and Edwin Wang --
Pharmacogenetic studies in pediatric acute myeloid leukemia / Neha S. Bhise, Lata Chauhan, and Jatinder K. Lamba --
Pharmacogenomics of antiretroviral drugs / Chonlaphat Sukasem, Apichaya Puangpetch, and Sadeep Medhasi --
Population stratification and its implications : lessons from genome-wide studies / Sheikh Nizamuddin, Rakesh Tamang, and Kumarasamy Thangaraj --
How to solve genetic disease on a population scale / Barry Merriman --
Economics of personalized medicine / Katherine Payne and Martin Eden.
Responsibility: edited by Krishnarao Appasani, GeneExpression Systems, Inc. ; forewords by Stephen W. Scherer, Universtiy of Toronto, Canada and Peter M. Visscher, University of Queensland, Australia.

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'Genome-Wide Association Studies: From Polymorphism to Personalized Medicine, edited by Krishnarao Appasani, summarizes most elegantly the contributions of GWAS as a major discovery tool linking Read more...

 
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