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Good cascade impactor practices, AIM and EDA for orally inhaled products

Autor: Terrence P Tougas; Jolyon P Mitchell; Svetlana A Lyapustina
Editora: New York : Springer, 2013.
Edição/Formato   e-book : Documento : InglêsVer todas as edições e formatos
Base de Dados:WorldCat
Resumo:
The purpose of this publication is to introduce a new, simpler and more effective way in which to interpret pharmaceutical aerosol particle size data from orally inhaled products (OIPs). Currently, the compendial and regulatory requirements dictate the need for measurements by full resolution multi-stage cascade impactor (CI), a process that is demanding for the operator, time consuming, prone to experimental error,  Ler mais...
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Gênero/Forma: Electronic books
Formato Físico Adicional: Print version:
Good cascade impactor practices, AIM and EDA for orally inhaled products
(OCoLC)824726203
Tipo de Material: Documento, Recurso Internet
Tipo de Documento: Recurso Internet, Arquivo de Computador
Todos os Autores / Contribuintes: Terrence P Tougas; Jolyon P Mitchell; Svetlana A Lyapustina
ISBN: 9781461462965 1461462967
Número OCLC: 839807002
Descrição: 1 online resource.
Conteúdos: Introduction / Terrence P. Tougas, Jolyon P. Mitchell --
Current Approaches to APSD Measurements of OIPs Based on Inertial Impaction / Jolyon P. Mitchell, Daryl L. Roberts --
Physical Causes of APSD Changes in Aerosols from OIPs and Their Impact on CI Measurements / Helen Strickland, Beth Morgan --
Good Cascade Impactor Practices / Jolyon P. Mitchell --
The AIM and EDA Concepts: Why They Are Needed and How They Fit Together / Jolyon P. Mitchell, Terrence P. Tougas --
Product Life Cycle Approach to Cascade Impaction Measurements / Richard Bauer, J. David Christopher --
Theoretical Basis for the EDA Concept / Terrence P. Tougas, Jolyon P. Mitchell --
Performance Characterization of EDA and Its Potential to Improve Decision Making in Product Batch Release / J. David Christopher, Helen Strickland --
Verification of the EDA Concept Through an Assessment of Theoretical Failure Modes, Failure Mode Analysis, and Case Studies with Real Data / Helen Strickland, Beth Morgan --
Validating AIM-Based Instrumentation and Associated Measurement Techniques / Mark Copley, Jolyon P. Mitchell --
The Regulatory and Compendial Pathways to Acceptance for AIM and EDA Concepts / Steven C. Nichols, Jolyon P. Mitchell --
Applying the AIM Concept in Support of Developing Improved In Vitro-In Vivo Relationships for OIPs / Jolyon P. Mitchell, Mark Copley --
Future Directions for the AIM and EDA Concepts / Terrence P. Tougas, Jolyon P. Mitchell --
Conclusions / Terrence P. Tougas, Svetlana A. Lyapustina.
Responsabilidade: edited by Terrence P. Tougas, Jolyon P. Mitchell, Svetlana A. Lyapustina.
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Resumo:

Offering a simpler way to interpret aerosol particle size data from orally inhaled products, this book describes mutually-independent efficient data analysis (EDA) metrics that can be derived from  Ler mais...

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