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Graft-vs.-host disease

Author: James L M Ferrara; Kenneth R Cooke; H Joachim Deeg
Publisher: New York : Marcel Dekker, ©2005.
Series: Clinical allergy and immunology, v. 19.
Edition/Format:   Print book : English : 3rd edView all editions and formats
Summary:
As they appeared in the first edition of this reference, some of the detailed descriptions of graft-vs.-host disease (GVDH) were impenetrable to readers who lacked specialty training in immunology; a field that has exploded in the last decade. To ameliorate the problem, the new edition includes an introductory series of chapters that review aspects of immunobiology necessary to the understanding of GVDH. Subsequent  Read more...
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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: James L M Ferrara; Kenneth R Cooke; H Joachim Deeg
ISBN: 0824754727 9780824754723
OCLC Number: 58598590
Description: xvii, 645 pages : illustrations ; 26 cm
Contents: The Pathophysiology of Graft-vs.-Host Disease. Animal Models of Graft-vs.-Host Disease. Graft-vs.-Host Disease as a Th1-Type Process: Regulation by Th2-Type Cells. Role of T-Cell Costimulation and Regulatory Cells in Allogeneic Hematopoietic Cell Transplantation. Chemokines and Graft-vs.-Host Disease. Graft-vs.-Leukemia Effects. The Immune System in Graft-vs.-Host Disease: Target and Effector Organ. Pathology and Pathogenesis of Cutaneous Graft-vs.-Host Disease. Graft-vs.-Host Disease of the Liver. Intestinal Graft-vs.-Host Disease. The Pathophysiology of Lung Injury After Hematopoietic Stem Cell Transplantation. Clinical Spectrum of Acute Graft-vs.-Host Disease. Role of Minor Histocompatibility Antigens in the Development of Graft-vs.-Host Disease and Graft-vs.-Leukemia Reactivity. Advances in Tissue Typing and Their Potential Impact on GVHD Incidence and Severity. Immunosuppression and Immunophilin Ligands: Cyclosporin, Tacrolimus, and Sirolimus. Prophylaxis and Treatments of Acute Graft-vs.-Host Disease. Graft Manipulation to Prevent Graft-vs.-Host Disease. Graft-vs.-Host Disease in Nonmyeloablative Transplant. Adoptive Immunotherapy in Stem Cell Transplantation. Clinical Spectrum and Therapeutic Approaches to Chronic Graft-vs.-Host Disease. Recent Advances and Future Directions.
Series Title: Clinical allergy and immunology, v. 19.
Responsibility: edited by James L. Ferrara, Kenneth R. Cooke, H. Joachim Deeg.
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Abstract:

With contributions from more than 40 leading authorities, this third edition explores the immunobiology, pathophysiology, and clinical manifestations of graft-versus-host disease (GVHD) - offering  Read more...

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"...This excellent book gives a comprehensive account of GvHD that will be an invaluable source of reference for transplantation biologists and all clinicians involved in bone marrow Read more...

 
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