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Growth factors and receptors : a practical approach

Author: Ian McKay; Kenneth D Brown
Publisher: Oxford [England] ; New York : Oxford University Press, 1998.
Series: Practical approach series, 194.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

Provides comprehensive protocols for studies of growth factors and their interactions with receptors. It covers a wide range, from simple analytical techniques to sophisticated in vivo applications  Read more...

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Genre/Form: Laboratory Manuals
Laboratory manuals
Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Ian McKay; Kenneth D Brown
ISBN: 0199636478 9780199636471 019963646X 9780199636464
OCLC Number: 38249246
Description: xxii, 266 pages : illustrations ; 24 cm.
Contents: 1. Engineered growth factors and receptors, and their applications ; 2. Engineering of novel neurotrophins ; 3. Designing new agonists.antagonists of growth factor receptors - the rational design of a super-antagonist of the IL-6 receptor ; 4. A Chimeric approach for studying receptor-binding domains in EGF-like molecules ; 5. Structure-activity relationships of chemokines ; 6. Generation and selection of RNA ligands that inhibit interaction of vascular permeability factor/vascular endothelial growth factor (VPF/VEGF) to its receptor ; 7. Immunolocalisation and RT-PCR for detection and quantification of growth factor and gene expression ; 8. Defining growth factor function through tissue-specific expression of dominant-negative receptor mutants ; 9. Growth factor-toxin chimeras and their applications ; 10. Gene therapy applications of growth factors ; Appendix 1 ; Appendix 2 ; Appendix 3
Series Title: Practical approach series, 194.
Responsibility: edited by Ian A. McKay and Kenneth D. Brown.
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