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|Additional Physical Format:||Print version:
Symposium, CIBA Foundation.
Growth Factors in Biology and Medicine.
Hoboken : John Wiley & Sons, ©2009
|Material Type:||Document, Internet resource|
|Document Type:||Internet Resource, Computer File|
|All Authors / Contributors:||
CIBA Foundation Symposium
|Description:||1 online resource (296 pages).|
|Contents:||Growth factors in biology and medicine; Contents; Introduction; Growth factors in mammalian embryogen-esis; Discussion; The EGF receptor kinase: evidence for allos- teric activation and intramolecular self-phosphorylation; Discussion; Role of growth factors in oncogenesis: growth factor-proto-oncogene pathways of mitogenesis; Discussion; Signalling mitogene- sis in 3T3 cells: role of Ca*+-sensitive, phospholipid-dependent protein kinase; Discussion; The PDGF-inducible 'compe- tence genes': intracellular mediators of the mitogenic response; Discussion. Platelet-derived growth factor: its potential roles in wound-healing, atherosclerosis, neoplasia, and growth and developmentDiscussion; Nerve growth factor; Discussion; The role of haemopoietic cell growth factor (interleukin 3) in the development of haemopoietic cells; Discussion; Haemopoietic growth factors: structure and receptor interac- tions; Discussion; In vivo effects of the insulin-like growth factors (IGFs) in the hypophysectomized rat: comparison with human growth hormone and the possible role of the specific IGF carrier proteins; Discussion. Protein phosphorylation and growth controlDiscussion; Receptors for the phorbol ester tumour promoters; Discussion; Ectopic peptides released by a human mela- noma cell line that modulate the transformed phenotype; Discussion; A growth regula- tory factor that can both inhibit and stimulate growth; Discussion; Final general discussion Receptor modulation and signalling systems; Biological functions of growth factors; Medical aspects of growth factors; Index of contributors; Subject index.|
|Series Title:||Novartis Foundation Symposia.|