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Handbook of anticancer pharmacokinetics and pharmacodynamics

Author: Michelle A Rudek
Publisher: New York ; Heidelberg : Springer, 2014.
Series: Cancer drug discovery and development.
Edition/Format:   eBook : Document : English : Second editionView all editions and formats

This book offers a detailed, step-by-step guide to the successful design and approval of anticancer drugs. It covers all steps, from the identification of cancer-specific molecular targets to  Read more...


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Genre/Form: Electronic books
Handbooks and manuals
Handbooks, manuals, etc
Additional Physical Format: Print version:
Handbook of anticancer pharmacokinetics and pharmacodynamics
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Michelle A Rudek
ISBN: 9781461491354 1461491355
OCLC Number: 869463069
Notes: Originally published by Human Press, Totowa, 2004.
Description: 1 online resource (xviii, 900 pages) : illustrations.
Contents: Molecular TargetsAnnunziata, Christina M. (et al.) Preclinical Screening for New Anticancer AgentsBurger, Angelika M. (et al.)Natural Product ScreeningMcKee, Tawnya C. (et al.)Defining the Starting Dose: Should It Be mg/kg, mg/mGao, Bo (et al.)Phase 0 Trials in OncologyKummar, Shivaani (et al.)Phase I Trials in Oncology: Design and EndpointsGlen, Hilary (et al.)Quantitative Analytical Methods: Development and Clinical ConsiderationsGardner, Erin R.Validation and Control of Bioanalytical MethodsKarnes, H. Thomas (et al.)Anticancer Clinical Pharmacology OverviewDandamudi, Uday B. (et al.)Pharmacokinetic ModelingLi, Jing (et al.)PharmacometricsBrar, Satjit S. (et al.)Pharmacodynamic ModelingBauer, Kenneth S. (et al.)Protein BindingSparreboom, Alex (et al.)Metabolism (Non-CYP Enzymes)Jamieson, David (et al.)Pharmacogenomics and Cancer Therapy: Somatic and Germline PolymorphismsPatel, Jai N. (et al.)Cytochrome P450Ando, YuichiPolymorphisms in Genes of Drug Targets and MetabolismBohanes, Pierre (et al.)DNA Repair: ERCC1, Nucleotide Excision Repair, and Platinum ResistanceReed, Eddie (et al.)Drug InteractionsRivory, Laurent P.ABC Transporters: Involvement in Multidrug Resistance and Drug DispositionMassey, Paul R. (et al.)Solute CarriersHo, Richard H. (et al.)High-Throughput Platforms in Drug Metabolism and Transport PharmacogeneticsEnglish, Bevin C. (et al.)Intrathecal AdministrationKilburn, Lindsay B. (et al.)MicrodialysisCombest, Austin J. (et al.)Regional Drug Delivery for Inoperable Pulmonary MalignanciesSchrump, David S.Blood-Brain Barrier and CNS MalignancyBalmanoukian, Ani (et al.)Radiation and Altering Clinical PharmacologySmart, DeeDee (et al.)Therapeutic Cancer Vaccines: An Emerging Approach to Cancer TreatmentMadan, Ravi A. (et al.)Recombinant ImmunotoxinsKreitman, Robert J.Monoclonal AntibodiesBai, Shuang (et al.)Clinical Pharmacology in PediatricsTagen, Michael (et al.)Clinical Pharmacology in the Older AdultSlattum, Patricia W. (et al.)Organ Dysfunction Trials: Background, Historical Barriers, Progress in Overcoming Barriers, and Suggestions for Future TrialsKummar, Shivaani (et al.)Drug Formulations: How these Affects Anticancer DrugLagas, Jurjen S. (et al.)Nanotechnology in CancerJanat-Amsbury, Margit M. (et al.)Imaging in Drug DevelopmentKurdziel, Karen A. (et al.)Exposure-Response Relationships of Anticancer Agents: Application in Drug Development and Drug LabelRahman, AtiqurThe Role of Phase III Trials in Modern Drug DevelopmentMurphy, Janet E. (et al.)Clinical Trial Designs for Approval of New Anticancer AgentsChadha, Manpreet K. (et al.)Clinical PharmacogeneticsSachidanandam, Kamakshi (et al.)
Series Title: Cancer drug discovery and development.
Responsibility: M.A. Rudek [and others].


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" invaluable overview of the experimental and clinical processes that lead to anticancer drugs, creating a single indispensable reference that covers all the steps from the identification of Read more...

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