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Handbook of chemical glycosylation : advances in stereoselectivity and therapeutic relevance
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Handbook of chemical glycosylation : advances in stereoselectivity and therapeutic relevance

著者: Alexei V Demchenko
出版商: Weinheim : Wiley-VCH, ©2008.
版本/格式:   图书 : 英语查看所有的版本和格式
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Since glycosidic linkage is one of the major challenges in carbohydrate chemistry, this book on recent developments fulfils a great need in covering the chemistry necessary to synthesize exact copies  再读一些...

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材料类型: 互联网资源
文件类型: 书, 互联网资源
所有的著者/提供者: Alexei V Demchenko
ISBN: 9783527317806 3527317805
OCLC号码: 174131473
描述: xxi, 501 p. : ill. ; 25 cm.
内容: Preface. List of Contributors. 1 General Aspects of the Glycosidic Bond Formation (Alexei V. Demchenko). 1.1 Introduction. 1.2 Major Types of O-Glycosidic Linkages. 1.3 Historical Development: Classes of Glycosyl Donors. 1.4 General Reaction Mechanism. 1.5 Anomeric Effects. 1.6 Stereoselectivity of Glycosylation. 1.7 Special Cases of Glycosylation. 1.8 Glycosylation and Oligosaccharide Sequencing. 1.9 Conclusions and Outlook. 2 Glycoside Synthesis from Anomeric Halides. 2.1 Glycosyl Fluorides (Shin-ichiro Shoda). 2.2 Glycosyl Chlorides, Bromides and Iodides (Suvarn S. Kulkarni, Jacquelyn Gervay-Hague). 3 Glycoside Synthesis from 1-Oxygen Substituted Glycosyl Donors. 3.1 Hemiacetals and O-Acyl/Carbonyl Derivatives (Daniel A. Ryan, David Y. Gin). 3.2 Glycoside Synthesis from 1-Oxygen-Substituted Glycosyl Imidates (Xiangming Zhu, Richard R. Schmidt). 3.3 Anomeric Transglycosylation (Kwan-Soo Kim, Heung-Bae Jeon). 3.4 Phosphates, Phosphites and Other O-P Derivatives (Seiichi Nakamura, Hisanori Nambu, Shunichi Hashimoto). 4 Glycoside Synthesis from 1-Sulfur/Selenium-Substituted Derivatives. 4.1 Thioglycosides in Oligosaccharide Synthesis (Wei Zhong, Geert-Jan Boons). 4.2 Sulfoxides, Sulfimides and Sulfones (David Crich, Albert A. Bowers). 4.3 Xanthates, Thioimidates and Other Thio Derivatives (Wieslaw Szeja, Grzegorz Grynkiewicz). 4.4 Selenoglycosides (Robert A. Field). 5 Other Methods for Glycoside Synthesis. 5.1 Orthoesters and Related Derivatives (Bert Fraser-Reid, J. Cristobal Lopez). 5.2 Other Methods for Glycoside Synthesis: Dehydro and Anhydro Derivatives (David W. Gammon, Bert F. Sels). 5.3 Miscellaneous Glycosyl Donors (Kazunobu Toshima). 5.4 The Twenty First Century View of Chemical O-Glycosylation (Thomas Ziegler). Index.
责任: edited by Alexei V. Demchenko.

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I recommend this monograph to all those who deal with carbohydrate chemistry or wish to do so. (Angewandte Chemie, July 7, 2008) "An excellent compilation of chemical glycosylation methods...I read 再读一些...

 
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