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Handbook of clinical neurology. Volume 104, 3rd series, Neuro-oncology, Part I

Author: Michael J Aminoff; François Boller; D F Swaab; Wolfgang Grisold; Riccardo Soffietti
Publisher: Amsterdam : Elsevier, 2012.
Series: Handbook of clinical neurology.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
This volume highlights recent developments in neuro-oncology that are not only increasing the survival rate of patients, but also improving their quality of life. Through an in-depth exploration of new therapies, including advanced diagnostic tools and a fresh perspective on molecular biology, immunology, and the clinical aspects of tumors, clinicians will gain a critical understanding of emerging therapies and  Read more...
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Genre/Form: Electronic books
Handbooks and manuals
Electronic book
Handbooks, manuals, etc
Additional Physical Format: Print version:
Grisold, Wolfgang.
Neuro-Oncology Part I : Handbook of Clinical Neurology (Series editors: Aminoff, Boller and Swaab).
Burlington : Elsevier Science, ©2012
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Michael J Aminoff; François Boller; D F Swaab; Wolfgang Grisold; Riccardo Soffietti
ISBN: 9780444534958 0444534954
OCLC Number: 815483574
Description: 1 online resource (xix, 434 pages) : illustrations.
Contents: Front Cover; Neuro-Oncology; Copyright; Available titles; Foreword; Preface; List of contributors; Contents of Part I; Contents of Part II; Section 1: Basic Principles; Chapter 1: Epidemiology of primary central nervous system tumors; Introduction; Descriptive Epidemiology Of adult Malignant and Nonmalignant Central Nervous System Tumors; Incidence and Mortality; Temporal Trends; Survival; Descriptive Epidemiology of Childhood Central Nervous System Tumors; Incidence and Mortality; Temporal Trends; Survival; Genetic Epidemiology; Genetic Syndromes; Familial Aggregation. Molecular Genetic InvestigationsEnvironmental Exposures; Ionizing Radiation; Electromagnetic Fields; Mobile Phones; Smoking; Diet; Occupation; Medications; Beauty Products; Allergy; Infectious Agents; References; Chapter 2: Molecular biology of brain tumors; Introduction; Genetic Alterations and Pathogenesis in Gliomas; Diffuse Astrocytoma; Diffuse Astrocytoma to Anaplastic Astrocytoma; Transition From Anaplastic Astrocytoma To glioblastoma Multiforme; Oligodendroglial Tumors; Predictive and Prognostic Molecular Markers in Glioma; Predictive Versus Prognostic. Methylguanine-Dna Methyltransferase MethylationEpidermal Growth Factor Receptor and Phosphoinositide 3-kinase Pathway; Ykl-40; Chromosome 1p/19q Deletion In oligodendroglioma; Proliferation Markers; Microarray Profiling; Microarray Technology; Microarray Profiling Identifies Molecular Subsets of Glioma; Molecular Genetics of Meningioma; Benign/grade I Meningioma; Anaplastic/grade Iii Meningioma; Summary; References; Chapter 3: Angiogenesis and invasion in cancer; Introduction; Basic Mechanisms of Vascular development; The Angiogenic Switch; Key Players in the Angiogenic Process. Lymphangiogenesis: a New Field In angiogenesis ResearchGeneral Aspects of Tumor Angiogenesis and Lymphangiogenesis; Angiogenesis and Brain Malignancy; Invasion and Its Relation To angiogenesis in Malignant Brain Tumors; Fibronectin; Proteases and Their Inhibitors; c-Met; References; Chapter 4: Immunology of brain tumors; Introduction; General Principles of Immunology; Immunology in the Central Nervous System; Interactions of Tumor Cells With immune Cells; The Controversial Role Of microglial Cells; Tumor-derived Immunosuppression; Transforming Growth Factor-beta. Nonclassical Major Histocompatibility Complex Class I MoleculesFurther Immunosuppressive Factors; Summary and Conclusions; References; Chapter 5: Blood-brain barrier and brain edema; The Blood-brain Barrier; Physiology of the Blood-brain Barrier; Circumventing the Blood-brain Barrier; Brain Tumor Edema; Pathophysiology of Brain Tumor Edema; Tumor-specific Aspects of Edema; Therapy-associated Brain Tumor Edema; Clinical Presentation of Brain Tumor Edema; Imaging of Brain Tumor Edema; Management of Brain Tumor Edema; Complications of Edema Therapy; References; Chapter 6: Stem cells in gliomas.
Series Title: Handbook of clinical neurology.
Other Titles: Neuro-oncology
Responsibility: series editors Michael J. Aminoff, Franȯis Boller and Dick F. Swaab ; volume editors Wolfgang Grisold and Riccardo Soffietti.

Abstract:

Offers developments in neuro-oncology that are increasing the survival rate of patients, and also improving their quality of life. This title is suitable for clinicians for summarizing the state of  Read more...

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