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Handbook of microdialysis : methods, applications, and perspectives

Author: B H C Westerink; Thomas Ivo Franciscus Hubert Cremers
Publisher: Amsterdam ; Boston : Elsevier/Academic Press, 2007.
Series: Handbook of behavioral neuroscience, v. 16.
Edition/Format:   Print book : English : 1st edView all editions and formats
Summary:
"Microdialysis is one of the most important in vivo sampling methods in physiology and pharmacology. It is used to determine the chemical components of the fluid in the extracellular space of tissues. The technique is now well established in neuroscience research and is used excessively in behavioral neuroscience to determine the concentrations and identities of molecules in brain tissues, and their change due to  Read more...
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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: B H C Westerink; Thomas Ivo Franciscus Hubert Cremers
ISBN: 9780444522764 044452276X
OCLC Number: 70775786
Description: xiv, 697 pages : illustrations.
Contents: Section 1. Interpretation and Significance --
1.1. What did we learn from microdialysis? / Trevor Sharp and Tyra Zetterstrom --
1.2. Microdialysis of glutamate and GABA in the brain: analysis and interpretation / Ben H.C. Westerink, Kieran Rea, Weite H. Oldenziel and Thomas I.F.H. Cremers --
1.3. Insights into glutamate physiology: contribution of studies utilizing in vivo microdialysis / David A. Baker and Peter W. Kalivas --
1.4. The validity of intracerebral microdialysis / Kevin C. Chen --
1.5. Microdialysis in the brain of anaesthetized vs. freely moving animals / M.A. de Souza Silva, C.P. Muller and J.P. Huston --
1.6. Quantitative aspects of brain microdialysis: insights from voltammetric measurements of dopamine next to microdialysis probes / Adrian C. Michael --
Section 2. Methods --
2.1. New methodological aspects of microdialysis / Jan Kehr --
2.2. Principles of quantitative microdialysis / Peter M. Bungay, Paul F. Morrison, Robert L. Dedrick, Vladimir I. Chefer and Agustin Zapata --
2.3. Automation of blood and microdialysis sampling: combinatorial pharmacology / Peter T. Kissinger --
2.4. Dopamine-acetylcholine interactions in the brain studied by in vivo microdialysis / George G. Nomikos --
2.5. Microdialysis as a platform for multidisciplinary strategies / J. Urenjak and T.P. Obrenovitch --
2.6. Ultraslow microfiltration and microdialysis for in vivo sampling: principle, techniques, and applications / Kirsten D. Huinink and Jakob Korf --
Section 3. Analytical Chemical Aspects of Microdialysis --
3.1. Liquid chromatographic methods used for microdialysis: an overview / Sophie Sarre and Yvette Michotte --
3.2. Microdialysis coupled with liquid chromatography/mass spectrometry / Malin Andersson and Richard M. Caprioli --
3.3. Improvement of the temporal resolution of brain microdialysis: sampling in seconds / Luis Hernandez, Sergio Rossell, Sonia Tucci, Daniel Paredes and Pedro Rada --
3.4. In vivo peptidomics: discovery and monitoring of neuropeptides using microdialysis and liquid chromatography with mass spectrometry / Robert T. Kennedy --
Section 4. Microdialysis and the Study of Behaviour --
4.1. Microdialysis to study the effects of stress on serotonin, corticosterone and behaviour / Astrid C.E. Linthorst --
4.2. Microdialysis of dopamine and norepinephrine during conditioning and operant behaviour / Matthijs G.P. Feenstra --
4.3. Microdialysis in the study of behavior reinforcement and inhibition / Pedro V. Rada, Ximena Paez, Luis F. Hernandez, Nicole M. Avena and Bartley G. Hoebel --
4.4. Changes in acetylcholine extracellular levels during cognitive processes / Giancarlo Pepeu and Maria G. Giovannini --
Section 5. CNS Pathology Models --
5.1. Microdialysis in genetically altered animals / Tatyana D. Sotnikova and Raul R. Gainetdinov --
5.2. The use of microdialysis in neuropsychiatric disease models / William T. O'Connor --
5.3. The use of microdialysis for the study of neurological disorders / Ilse Smolders and Yvette Michotte --
5.4. Online glucose and lactate monitoring during physiological and pathological conditions / Marianne Fillenz --
5.5. Microdialysis in pain research / Carl-Olav Stiller, Ernst Brodin and Bradley K. Taylor --
Section 6. Role of Microdialysis in Drug Development --
6.1. The role of microdialysis in drug discovery: focus on antipsychotic agents / M.J. Millan, F. Panayi, J.M. Rivet, B. Di Cara, L. Cistarelli, R. Billiras, S. Girardon and A. Gobert --
6.2. Use of microdialysis in drug discovery and development: industry and regulatory perspectives / Hans Rollema and Chandra S. Chaurasia --
6.3. The use of brain microdialysis in antidepressant drug research / Francesc Artigas and Albert Adell --
6.4. Microdialysis as a method to study blood-brain barrier transport mechanisms / Elizabeth C.M. de Lange --
6.5. Assaying protein-unbound drugs using microdialysis techniques / Tung-Hu Tsai --
6.6. Microdialysis for characterization of PK/PD relationships / Margareta Hammarlund-Udenaes --
6.7. Application of microdialysis in pharmacokinetic studies / Ronald J. Sawchuk and Belind W.Y. Cheung --
Section 7. Clinical Applications --
7.1. Microdialysis in clinical drug delivery studies / Martin Brunner and Markus Muller --
7.2. Transport of glucose to a probe in adipose tissue / K.J.C. Wientjes, K. Hoogenberg and A.J.M. Schoonen --
7.3. Neurochemical monitoring in neurointensive care using intracerebral microdialysis / Thomas Lieutaud, Frederic Dailler, Francois Artru and Bernard Renaud --
7.4. Microdialysis in the human brain: clinical applications / Urban Ungerstedt and Elham Rostami.
Series Title: Handbook of behavioral neuroscience, v. 16.
Responsibility: edited by Ben H.C. Westerink and Thomas I.F.H. Cremers.
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Abstract:

Microdialysis is one of the most important in vivo sampling methods in physiology and pharmacology. It is used to determine the chemical components of the fluid in the extracellular space of tissues.  Read more...

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"4 Stars. This is an excellent contribution to the field of microdialysis and is highly recommended for neurosurgical or neuroscience libraries."-Doody's

 
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