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Handbook of neurotoxicity

Author: Richard M Kostrzewa
Publisher: New York, NY : SpringerReference, 2014.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
The Handbook of Neurotoxicity is a reference source for identifying, characterizing, instructing on use, and describing outcomes of neurotoxin treatments - to understand mechanisms associated with toxin use; to project outcomes of neurotoxin treatments; to gauge neurotoxins as predictors of events leading to neurodegenerative disorders and as aids to rational use of neurotoxins to model disease entities.  Read more...
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Genre/Form: Electronic books
Handbooks and manuals
Handbooks, manuals, etc
Additional Physical Format: Printed edition:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Richard M Kostrzewa
ISBN: 9781461458364 1461458366 1461458358 9781461458357
OCLC Number: 881315260
Notes: Includes index.
Description: 1 online resource (xxxviii, 2371 pages) : illustrations (some color)
Contents: Glutamate as a neurotoxin, --
methamphetamine and mdma neurotoxicity: biochemical and molecular mechanisms --
microglia: neuroprotective and neurodestructive properties --
neuroprotection in demyelinating diseases: the therapeutic potential of the neurotrophins --
neurotrophic factors and ethanol neurotoxicity --
neurotrophic factors and neuroaids: a lesson from brain-derived neurotrophic factor --
neurotrophins and p75ntr in axonal regeneration and myelination --
neurotrophins and pain --
neurotrophin signalling in cancer --
ngf and immune regulation --
ngf/p75 in cell cycle and tetraploidy --
p75 in neuronal death --
p75ntr processing and signaling: functional role --
p75ntr-a molecule with multiple functions in amyloid-beta metabolism and neurotoxicity --
rcsn cell system for identifying dopaminergic neurotoxicity --
seizures tip the balance of neurotrophin signaling towards neuronal death --
survey of selective neurotoxins --
synthesis, trafficking and release of bdnf --
the nature of dsp-4-induced neurotoxicity --
trafficking of neurotrophins and their receptors and pathological significance --
trpv1 activators ("vanilloids") as neurotoxins --
experimental approach to alzheimer disease --
iron-induced dopaminergic cell death in vivo as a model of parkinsońs disease --
molecular, cellular and behavioural effects produced by perinatal asphyxia: protection by poly (adp-ribose) polymerase 1 (parp-1) inhibition --
mptp: advances from an evergreen neurotoxin --
multifunctional compounds for parkinsons disease and alzheimers disease --
nanomedicines for nervous system diseases --
neurodegenerative aspects of multiple system atrophy --
neurotoxic profiles of designer-drugs --
pathophysiology of obsessive-compulsive disorder: insights from normal function and neurotoxic effects of drugs, infection and brain injury --
physical exercise as intervention in parkinsonism --
protective agents in parkinsońs disease: caffeine and adenosine a2a receptor antagonists --
stem cell therapies for age associated neurodegeneration --
aids --
excitotoxicity and axon degeneration --
glutamate neurotoxicity related to energy failure --
neuroprotection by kynurenine metabolites --
pain --
quinolinate and related excitotoxins: mechanisms of neurotoxicity and disease relevance --
role of ionotropic glutamate receptors in neurodegenerative and other disorders --
tardive dyskinesia: outcome of antipsychotic treatment and brain damage? --
the concept of excitotoxicity via glu-r --
the pathogenesis of alzheimers disease --
5,6- and 5,7-dihydroxytryptamines as serotoninergic neurotoxins --
neurotoxicity of methamphetamine --
neurotoxic effects, mechanisms and outcome of 192-igg saporin --
neurotrophic therapy for als/ mnd --
cancer-mediated neurotoxicity --
neurotoxicity in psychostimulant and opiate addiction --
excitotoxicity in hiv associated neurocognitive disorders --
necroptosis, a potential therapeutic target for neurological disorders --
epilepsy --
excitotoxicity and amyotrophic lateral sclerosis --
excitotoxicity in the pathogenesis of autism --
glutamate neurotoxicity, transport and alternate splicing of transporters --
glutamatergic receptors in parkinsons̀ disease --
ionotropic receptors in the central nervous system and neurodegenerative disease --
lead & excitotoxicity --
molecular mechanism and effects of clostridial neurotoxins --
ms & excitotoxicity --
neuroprotectants targeting nmda receptor signaling --
neurotoxicity and als: insights into pathogenesis --
schizophrenia --
neurotoxic vulnerability underlying schizophrenia spectrum disorders --
glutamate in the pathogenesis of gliomas --
neurotoxicity and neuroprotection in spinal cord injury --
drug abuse neurotoxicity: alcohol and nicotine as developmental stressors --
botulinum neurotoxins as therapeutics --
mptp neurotoxicity: actions, mechanisms and animal modeling of parkinsons disease --
endogenous kynurenic acid and neurotoxicity --
the potential therapeutic effects of statins in alzheimer's disease --
drug treatments for alzheimeŕs disease: hopes and challenges --
glutamate and neurodegeneration in the retina --
stroke --
brain trauma neuroprotection --
neuroprotective strategies in amyotrophic lateral sclerosis: modulation of neurotransmittory and neurotrophic input to motor neurons --
the role of neurotoxicity in depression --
advances in stem cell research for parkinson disease --
neurotoxicity in huntington disease --
fusion models and f́usioningìn parkinsonism: protection and restoration by exercise --
neurotoxicity: a complex multistage process involving different mechanisms.
Responsibility: Richard M. Kostrzewa, editor.
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