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The heart and circulation : an integrative model

Author: Branko Furst
Publisher: London : Springer, 2013. ©2014
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
What drives the circulation? In this comprehensive review of existing circulation models, the conventional view that the heart is a pressure-propulsion pump is challenged. The existing models fail to explain an increasing number of observed circulatory phenomena. A unifying circulation model is proposed in which the blood, responding to metabolic demands of the tissues, is the primary regulator of cardiac output.  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Furst, Branko.
Heart and Circulation : An Integrative Model.
Dordrecht : Springer, ©2013
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Branko Furst
ISBN: 9781447152774 1447152778 144715276X 9781447152767
OCLC Number: 857412891
Description: 1 online resource (XXIX, 226 pages) : illustrations
Contents: Part I. Embryonic Circulation Early Embryo Circulation --
The Onset of Circulation --
Hemodynamics of the Early Embryo Circulation --
Flow Patterns in the Early Embryo Circulation --
Is There a Circulation Without a Heart? --
Embryo Heart is not a Peristaltic Pump --
Flow Perturbation Experiments --
Heart Rate Perturbations --
The Heart as Generator of Pressure --
Ventriculo-Vascular Interaction --
A Brief Comparative Phylogeny --
Evolutionary Aspect of the Rhythmical System --
Part II. Mature Circulation --
Functional Morphology of the Heart --
Regulation of Cardiac Output --
Circulatory and respiratory functions of the blood --
Models of the Heart --
Cardiovascular Response during Exercise --
Hemodynamic Effects of Aortic Occlusion --
Increased Pulmonary Flows --
Single Ventricle Physiology --
Blood as an Organ.
Responsibility: Branko Furst.

Abstract:

What drives the circulation? In this comprehensive review of existing circulation models, the conventional view that the heart is a pressure-propulsion pump is challenged. The existing models fail to explain an increasing number of observed circulatory phenomena. A unifying circulation model is proposed in which the blood, responding to metabolic demands of the tissues, is the primary regulator of cardiac output. This new model arises from accumulated clinical and experimental evidence. The heart, rather than being an organ of blood propulsion, assumes a secondary role and generates pressure by impeding the flow of blood. This is supported by examples from the fields of early embryonic circulation, comparative phylogeny, functional morphology, exercise physiology and a range of clinical scenarios. The Heart and Circulation: An Integrative Model offers a paradigm shift in the understanding of circulatory phenomena. It will become a valuable resource for all those clinicians, researchers, educators and students who, having been confronted with the paradox of the circulation, are looking for a broader interpretation.

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"Dr. Furst has commendably reviewed the origin and historical development of the heart-as-a-pump concept and amassed, as well, a very considerable weight of evidence undermining it and supporting an Read more...

 
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