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High-Dose Cancer Therapy : Pharmacology, Hematopoietins, Stem Cells.

Author: James O Armitage; Karen H Antman
Publisher: Philadelphia : Wolters Kluwer Health, 1999.
Edition/Format:   eBook : Document : English : 3rd edView all editions and formats
Summary:
The Third Edition of this comprehensive reference has been overhauled, with 28 of 50 chapters either completely updated or rewritten by new authors. This reflects the fact that this treatment modality is now the standard of care for a variety of cancers, including 10-20,000 cases/year of various forms of leukemia, multiple myeloma, Hodgkin's disease, non-Hodgkin's lymphoma, lung cancer, ovarian cancer, etc. High  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Armitage, James O.
High-Dose Cancer Therapy : Pharmacology, Hematopoietins, Stem Cells.
Philadelphia : Wolters Kluwer Health, ©1999
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: James O Armitage; Karen H Antman
ISBN: 9781469874531 1469874539
OCLC Number: 913799496
Description: 1 online resource (973 pages)
Contents: Cover; Copyright; Dedication; Editors; Foreword to the First Edition; Preface; Contents; Section I Strategies for the Use of Agents at High Dose; 1 Pharmacologic Strategies for High-Dose Therapy; 2 Preclinical Models for High-Dose Therapy; 3 Pharmacokinetics; 4 What Is the Best Strategy for Autologous Hematopoietic Stem Cell Transplantation in Cancer; 5 Strategies for the Use of Total-body Irradiation as Systemic Therapy in Hematologic Malignancies; 6 Radioimmunotherapy; 7 Immune Adjuvant Therapy Post High-Dose Therapy. 8 A Health Policy Perspective on High-Dose Cancer Therapy: Cost, Effectiveness, and Cost-Effectiveness9 Quality of Life after Bone Marrow Transplantation; 10 Gene Therapy; Section II Reestablishing Hematopoiesis after Dose-Intensive Therapy Transplantation; 11 The Hematopoietic Microenvironment; 12 Hematologic Reconstitution after Allogeneic Hematopoietic Cell Transplantation; 13 Allogeneic Cord Blood Hematopoietic Stem Cells Transplants in Malignancies; 14 Bone Marrow Transplantation Using Unrelated Donors; 15 Autologous Bone Marrow Transplantation. 16 Reestablishing Hematopoiesis with Peripheral Stem Cells17 Immunologic Reconstitution after High-Dose Chemoradiotherapy and Allogeneic or Autologous Bone Marrow or Peripheral Blood Hematopoietic Stem Cell Transplantation; Marrow Contamination; 18 Minimal Disease: Detection and Significance; 19 Negative and Positive Stem Cell Selection; 20 Stem Cell In Vitro Purging for Autologous Transplantation; Growth Factors; 21 Granulocyte-Macrophage Colony-Stimulating Factor; 22 Recombinant Human Granulocyte Colony-Stimulating Factor Support of the Cancer Patient; 23 Erythropoietin. 24 The Biology and Clinical Use of Stem Cell Factor25 Other Cytokines (IL-11, Thrombopoietin, flt-3 Ligand, and IL-3); Section III Laboratory and Clinical Support for Dose-Intensive Therapy; 26 The American Society of Clinical Oncology and American Society of Hematology Recommended Criteria for the Performance of Bone Marrow Transplantation; 27 Nursing for Patients Receiving High-Dose Chemotherapy with Hematopoietic Rescue; 28 Line Maintenance; 29 Blood Bank Support for Patients Undergoing High-Dose Chemotherapy; 30 Infectious Complications after High-Dose Chemotherapy. 31 Pulmonary Complications32 Hepatic Complications of Bone Marrow Transplantation; 33 Cardiovascular System and High-Dose Therapy; 34 Multiple Organ Dysfunction Syndrome; 35 Dermatology; 36 Genitourinary, Gastrointestinal, Endocrine, Nervous System, and Coagulation Complications; 37 Gonadal Complications; Section IV Clinical Applications of High-Dose Therapy; 38 High-Dose Therapy in Acute Myeloid Leukemia; 39 High-Dose Therapy in Acute Lymphoblastic Leukemia; 40 Chronic Myelogenous Leukemia; 41 Hematopoietic Stem Cell Transplantation for Chronic Lymphocytic Leukemia.

Abstract:

The Third Edition of this comprehensive reference has been overhauled, with 28 of 50 chapters either completely updated or rewritten by new authors. This reflects the fact that this treatment modality is now the standard of care for a variety of cancers, including 10-20,000 cases/year of various forms of leukemia, multiple myeloma, Hodgkin's disease, non-Hodgkin's lymphoma, lung cancer, ovarian cancer, etc. High dosage chemotherapy is now also used in advanced cases of breast cancer. It is now being done by private practitioners in most of the hospitals in the country from the community hospit.

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