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The hippo signaling pathway and cancer

Author: Moshe Oren; Yael Aylon
Publisher: New York, NY : Springer, ©2013.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
The Hippo signaling pathway is rapidly gaining recognition as an important player in organ size control and tumorgenesis. This volume presents virtually all aspects of tumor biology because members of the Hippo Pathway have been associated with numerous well-established cell signaling pathways, just to name a few; Rho, Wnt, TGFbeta and p53. Hippo signaling is not solely involved in regulating "classic" tumor  Read more...
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Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Moshe Oren; Yael Aylon
ISBN: 9781461462200 1461462207 1461462193 9781461462194
OCLC Number: 832729115
Notes: Includes index.
Description: 1 online resource.
Contents: Up-stream Components of Hippo Signaling --
Merlin and Angiomotin in Hippo-Yap Signaling / Chunling Yi, Joseph Kissil --
MST1/2 and Other Upstream Signaling that Affect Hippo Pathway Function / Julien Fitamant ... [et al.] --
YAP and TAZ --
YAP1 Uses Its Modular Protein Domains and Conserved Sequence Motifs to Orchestrate Diverse Repertoires of Signaling / Marius Sudol, Irwin H. Gelman, Jianmin Zhang --
Regulation of YAP and TAZ Transcription Co-activators / Fa-Xing Yu, Bin Zhao, Kun-Liang Guan --
Regulation of YAP and TAZ by Epithelial Plasticity / Stefano Piccolo, Michelangelo Cordenonsi --
Apoptosis and Hippo Signaling --
Hippo Pathway and Apoptosis / Garth Hamilton, Eric O'Neill --
YAP and p73: A Matter of Mutual Specificity in Tumor Suppression / Sara Donzelli, Sabrina Strano, Giovanni Blandino --
The c-Abl/YAP/p73 Apoptotic Module and the HIPPO Pathway / Nina Reuven, Yosef Shaul --
Cell Cycle and Hippo Signaling --
Hippo in Cell Cycle and Mitosis / Norikazu Yabuta, Hiroshi Nojima --
Mouse Models --
Hippo and Mouse Models for Cancer / Min-Chul Kim ... [et al.] --
Roles of Hippo Signaling During Mouse Embryogenesis / Hiroshi Sasaki --
Hippo Signaling and Stem Cells / Kriti Shrestha, Fernando D. Camargo --
Hippo Signaling and Organ Size Control / Randy L. Johnson --
Hippo Signaling in Heart Development / Todd Heallen ... [et al.] --
Cross-Talk with Other Pathways --
Cell Competition and the Hippo Pathway / Chiao-Lin Chen, Georg Halder --
Non-canonical Roles for the Hippo Pathway / Xaralabos Varelas.
Responsibility: Moshe Oren, Yael Aylon, editors.

Abstract:

This book explores virtually all aspects of tumor biology in relation to the Hippo Pathway. It gathers wide-ranging and burgeoning information into an accessible format and features timely research  Read more...

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