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Histone deacetylases : transcriptional regulation and other cellular functions

Author: Eric Verdin
Publisher: Totowa, N.J. : Humana Press, ©2006.
Series: Cancer drug discovery and development.
Edition/Format:   Print book : EnglishView all editions and formats
Database:WorldCat
Summary:

Summarizes the discoveries in the field of histone acetylation as a key regulatory mechanism for gene expression. This book describes the identification of the enzymes, the elucidation of the  Read more...

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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Eric Verdin
ISBN: 1588294994 9781588294999 1597450243 9781597450249
OCLC Number: 62216887
Description: xi, 340 pages : illustrations (some color) ; 24 cm.
Contents: Histone deacetylase 1 / Dominique Meunier and Christian Seiser --
Biochemistry of multiprotein HDAC complexes / Alejandro Vaquero, Michael Scher, and Danny Reinberg --
Biology of HDAC3 / Edward Seto --
Biology of HDAC8, a unique class I histone deacetylase / David Waltregny and Vincent Castronovo --
Regulation of muscle gene expression by histone deacetylases / Timothy A. McKinsey and Eric N. Olson --
Class IIA histone deacetylases : functions and regulation / Herbert G. Kasler and Eric Verdin --
Histone deacetylases in the response to misfolded proteins / J. Andrew McKee and Tso-Pang Yao --
Evolution of sirtuins from archaea to vertebrates / Roy A. Frye --
Structure of the SIR2 family of NAD+-dependent histone/protein deacetylases / Kehao Zhao and Ronen Marmorstein --
Enzymology of Sir2 proteins / Margie T. Borra and John M. Denu --
Class III protein deacetylases : homologs of yeast SIR2P / Bjoern Schwer [and others] --
HDAC inhibitors : discovery, development, and clinical impacts / Akihiro Ito, Norikazu Nishino, and Minoru Yoshida --
Cell cycle targets of histone deacetylase inhibitors / Brian Gabrielli --
HDAC inhibitors : an emerging anticancer therapeutic strategy / Paul Kwon, Meier Hsu, Dalia Cohen, and Peter Atadja.
Series Title: Cancer drug discovery and development.
Responsibility: edited by Eric Verdin.
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