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Hormones, genes, and cancer

Author: Brian E Henderson; B A J Ponder; Ronald K Ross
Publisher: Oxford ; New York : Oxford University Press, 2003.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:
Hormonal carcinogenesis is an important and controversial area of current research. In addition to accelerating existing cancers, can hormones play the role of primary carcinogens? How do genetic factors influence hormone-related cancer risk? Hormones, Genes, and Cancer addresses these questions. Over the past few decades, cancer research has focused on external environmental causes(e.g., tobacco smoke, viruses,  Read more...
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Material Type: Internet resource
Document Type: Book, Internet Resource
All Authors / Contributors: Brian E Henderson; B A J Ponder; Ronald K Ross
ISBN: 0195135768 9780195135763
OCLC Number: 49895248
Description: xiii, 450 pages, [4] pages of plates : illustrations (some color) ; 26 cm
Contents: Introduction and background --
Biosynthesis, transport, and metabolism of steroid hormones --
The nuclear receptor superfamily --
Genomic approaches to the genetics of hormone-responsive cancer --
Breast cancer: epidemiology and molecular endocrinology --
The impact of exogenous hormone use on breast cancer risk --
An overview of genetic predisposition and the search for predisposing genes for breast cancer --
Estrogen biosynthesis genes: P-450 aromatase --
Estrogen metabolism genes: HSD17B1 and HSD17B2 --
Breast cancer: intervention in BRCA1 and BRCA2 families --
Implications of hormones and hormonal risk factors on screening strategies --
Hormonal chemoprevention with tamoxifen and selective estrogen receptor modulators --
Other hormonal prevention strategies --
Progression from hormone-dependent to hormone-independent breast cancer --
Prostate cancer: epidemiology and molecular endocrinology --
Androgen receptor signaling in prostate cancer --
Hereditary prostate cancer: the search for major genes and the role of genes involved in androgen action --
Androgen-independent prostate cancer progression: mechanistic insights --
Hormonal therapies for prostate cancer --
Endometrial cancer: epidemiology and molecular endocrinology --
Ovarian cancer: epidemiology and molecular endocrinology --
Testicular cancer: epidemiology and molecular endocrinology.
Responsibility: [edited by] Brian E. Henderson, Bruce Ponder, Ronald K. Ross.
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Abstract:

Hormonal carcinogenesis is an important and controversial area of current research. In addition to accelerating existing cancers, can hormones play the role of primary carcinogens? How do genetic  Read more...

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"Overall, I wholeheartedly recommend Hormones, Genes, and Cancer to the physicians, investigators, and students in the fields of genetics, endocrinology, and oncology. I think each of them will find Read more...

 
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