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Host-parasite relationships and the Yersinia model

Author: Akira Wake; Herbert R Morgan
Publisher: New York : Springer-Verlag, ©1986.
Series: Springer series in molecular biology.
Edition/Format:   Print book : EnglishView all editions and formats
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Document Type: Book
All Authors / Contributors: Akira Wake; Herbert R Morgan
ISBN: 0387167250 9780387167251 3540167250 9783540167259
OCLC Number: 13822374
Description: xi, 329 pages : illustrations ; 24 cm.
Contents: I Virulence Factors and Their Genetic Control.- 1 Microorganisms.- 2 Host-Parasite Relationship.- 3 Localization of Virulence Determinants.- 4 Superficial Infection With or Without Toxinogenesis.- Example 1: Corynebacterium diphtheriae.- Example 2: Vibrio cholerae and Enterotoxinogenic Escherichia coli.- 5 Exudative (Partially Invasive) Infections.- Example 1: Staphylococcus aureus.- Example 2: Shigella dysenteriae.- 6 Invasive (Penetrating) Infections (Except Yersiniosis).- Viruses.- Rickettsiae.- Bacteria.- Example 1: Spirochetes.- Example 2: Mycobacterium tuberculosis.- Example 3: Salmonella.- Example 4: Listeria monocytogenes.- 7 Summary.- II Defense Mechanisms of Host Against Infection.- 1 Recognition by the Immune System.- 2 The Mechanisms for Maintenance of Self-Integrity.- 3 Superficial Defense.- Skin.- Cornea.- Mucous Membranes.- 4 The Role of Body Temperature: Fever and Reduced Iron.- 5 The Defensive Role of Normal Microbial Flora.- 6 The Nonspecific Humoral Components.- Complement System.- Transferrin and Lactoferrin.- Cytokines Including Prostaglandins, Thromboxans, and Leukotrienes.- Interferon (IFN).- 7 Specific Humoral Components: Immunoglobulins.- Structures of Immunoglobulins.- Biological Characteristic and Time Course of Each Class of Antibody Production.- 8 Genesis and Distribution of Cellular Components with Defensive Functions.- Polymorphonuclear Cells (PMN).- Basophils and Mast Cells.- Eosinophils (Acidophils).- Mononuclear Cells.- Lymphocytes and Their Functions.- Dendritic Cells (DC).- Platelet.- 9 Extracellular and Intracellular Destruction of Microorganisms.- Reticuloendothelial Systems (RES).- Phagocytosis.- Endocytosis.- Mechanisms for the Destruction of Microorganisms.- 10 Inflammation, as a Defense Mechanism.- Reaction of Blood Vessels.- Dynamics of Leukocytes in Inflammation.- Result of Inflammation.- 11 Genetic Regulation of Defense Mechanisms: Cell-Mediated Immunity in Particular.- T-Cell-Mediated Intracellular Destruction of Listeria Monocytogenes.- 12 Summary.- III The Yersinia-Host Relationship.- 1 Human Disease Caused by Yersinia.- 2 Virulence Factors of Yersinia pestis.- F1.- VW and Cal.- P1.- P.- Pu.- Interactions Among Plasmids and Their Influence on Virulence.- 3 Other Mechanisms of Yersinia Organisms Functioning for Expression of Their Virulence.- Endotoxin, i.e., Lipopolysaccharides of Yersinia Organisms.- How Yersinia Organisms Transport Iron that Enhances Virulence.- The Relationship of Arginine Metabolism with Y. pestis Virulence.- 4 Host Resistances to Yersinia Organisms - Immunology in Yersinia Infection.- Natural Resistance to Y. pestis Infection Expressed in the Strain Differences in Mice and Guinea Pigs.- Humoral Aspects of Anti-Y. pestis Acquired Immunity.- Cell-Mediated Immunity as Anti-Y. pestis Bactericidal Mechanisms.- Cooperative Protection Provided by Humoral and Cell-Mediated Immune Responses Against Y. pestis Infection.- The Strain Differences of Anti-Y. pestis Acquired Immunity in Mice and Guinea Pigs.- 5 The Phylogenetic Influence of Yersinia Infection on Human Major Histocompatibility Complex (HLA).- 6 Summary.- References.
Series Title: Springer series in molecular biology.
Responsibility: Akira Wake, Herbert R. Morgan.

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