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How science will help shape future clinical applications of probiotics.
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How science will help shape future clinical applications of probiotics.

Author: G Reid Affiliation: Canadian Research and Development Centre for Probiotics, Lawson Health Research Institute, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada. gregor@uwo.ca
Edition/Format: Article Article : English
Publication:Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2008 Feb 1; 46 Suppl 2: S62-6; discussion S144-51
Database:From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
Other Databases: British Library SerialsArticleFirstElsevier
Summary:
The recent increased interest in probiotics among clinicians has many causes, primarily the concern about the limitations of the current armamentarium of pharmaceutical agents. Although probiotics have been used mostly in dietary supplements and foods to maintain health, scientific and clinical studies are recognizing the potential of some probiotics to be therapeutic in function. Scientific breakthroughs in  Read more...
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Document Type: Article
All Authors / Contributors: G Reid Affiliation: Canadian Research and Development Centre for Probiotics, Lawson Health Research Institute, Schulich School of Medicine and Dentistry, The University of Western Ontario, London, Ontario, Canada. gregor@uwo.ca
ISSN:1058-4838
Language Note: English
Unique Identifier: 263984883
Awards:

Abstract:

The recent increased interest in probiotics among clinicians has many causes, primarily the concern about the limitations of the current armamentarium of pharmaceutical agents. Although probiotics have been used mostly in dietary supplements and foods to maintain health, scientific and clinical studies are recognizing the potential of some probiotics to be therapeutic in function. Scientific breakthroughs in understanding the source and composition of the human microbiota, the key nutritional factors that influence these microbes, and their immunomodulatory effects; the creation of disease-targeted recombinant strains; the isolation and characterization of signaling molecules that can modulate microbial biofilms and infectious processes; and advances in biomedical engineering that will provide new delivery systems for probiotics will shape the future of clinical applications of probiotics. In time and with rigorous documentation, some probiotics will likely find an important place in medical practice.

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