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Human Chromosomes : Structure, Behavior, and Effects

Author: Eeva Therman; Millard Susman
Publisher: New York, NY : Springer US, 1993.
Series: Springer Study Edition; Springer study edition
Edition/Format:   eBook : Document : English : Third editionView all editions and formats
Summary:
The third edition of this successful text provides students, researchers and technicians in the area of medicine, genetics and cell biology with a concise, understandable introduction to the structure and behavior of human chromosomes. It covers both basic and up-to-date material on normal and defective chromosomes. The mapping and molecular analysis of chromosomes is one of the most exciting and active areas of  Read more...
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Details

Genre/Form: Electronic books
Additional Physical Format: Print version:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Eeva Therman; Millard Susman
ISBN: 9781468405293 1468405292
OCLC Number: 859156667
Description: 1 online resource.
Contents: 1. Origins and Directions of Human Cytogenetics --
2. Structure of the Eukaryotic Chromosome and the Karyotype --
3. Mitotic Cycle and Chromosome Reproduction --
4. Methods in Human Cytogenetics --
5. Molecular Methods --
6. Longitudinal Differentiation of Eukaryotic Chromosomes --
7. Significance of Chromosome Bands --
8. Architecture and Function of the Eukaryotic Chromosome --
9. Chromosome Structural Aberrations --
10. Causes of Chromosome Breakage --
11. Chromosome Instability Syndromes --
12. Sister Chromatid Exchanges and Mitotic Crossing-Over --
13. Cell Fusion, Prematurely Condensed Chromosomes, and the Origin of Allocyclic Chromosomes --
14. Chromosome Arrangement in Interphase and in Differentiated Nuclei --
15. Modifications of Mitosis --
16. Chromosomal Differentiation of Cells --
17. Main Features of Meiosis --
18. Details of Meiosis --
19. Meiotic Abnormalities --
20. Human Sex Determination and the Y Chromosome --
21. Human X Chromosome --
22. Abnormal Human Sex Chromosome Constitutions --
23. Functional Structure of the Human X Chromosome --
24. Numerically Abnormal Chromosome Constitutions in Humans --
25. Structurally Abnormal Human Autosomes --
26. Reciprocal Translocations --
27. Robertsonian Translocations --
28. Double Minutes and Homogeneously Stained Regions --
29. Chromosomes and Oncogenes --
30. Chromosomal Development of Cancer --
31. Mapping of Human Chromosomes --
Index of Names.
Series Title: Springer Study Edition; Springer study edition
Responsibility: by Eeva Therman, Millard Susman.

Abstract:

The third edition of this successful text provides students, researchers and technicians in the area of medicine, genetics and cell biology with a concise, understandable introduction to the structure and behavior of human chromosomes. It covers both basic and up-to-date material on normal and defective chromosomes. The mapping and molecular analysis of chromosomes is one of the most exciting and active areas of modern biomedical research, and this book will be invaluable to scientists, students, technicians and physicians with an interest in the function and dysfunction of chromosomes. Reviews of previous editions have described this book as a "gem" and "an excellent text."

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