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Human drug metabolism : an introduction

Author: Michael D Coleman; Wiley InterScience (Online service)
Publisher: Oxford ; Hoboken, NJ : Wiley-Blackwell, ©2010.
Edition/Format:   eBook : Document : English : 2nd edView all editions and formats
Summary:
(Publisher-supplied data) Human Drug Metabolism, An Introduction, Second Edition provides an accessible introduction to the subject and will be particularly invaluable to those who already have some understanding of the life sciences. Completely revised and updated throughout, the new edition focuses only on essential chemical detail and includes patient case histories to illustrate the clinical consequences of  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Coleman, Michael D.
Human drug metabolism.
Oxford ; Hoboken, NJ : Wiley-Blackwell, ©2010
(OCoLC)495596457
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Michael D Coleman; Wiley InterScience (Online service)
ISBN: 9780470689332 0470689331 9780470689349 047068934X
OCLC Number: 613339185
Description: 1 online resource (xiv, 346 pages)
Contents: Front Matter --
Introduction --
Drug Biotransformational Systems-Origins and Aims --
How Oxidative Systems Metabolize Substrates --
Induction of Cytochrome P450 Systems --
Cytochrome P450 Inhibition --
Conjugation and Transport Processes --
Factors Affecting Drug Metabolism --
Role of Metabolism in Drug Toxicity --
Appendix A: Methods in Drug Metabolism --
Appendix B: Metabolism of Major Illicit Drugs --
Appendix C: Examination Techniques --
Appendix D: Summary of Major CYP Isoforms and their Substrates, Inhibitors and Inducers --
Suggested Further Reading --
Index.
Responsibility: Michael D. Coleman.

Abstract:

Human Drug Metabolism, An Introduction, Second Edition provides an accessible introduction to the subject and will be particularly invaluable to those who already have some understanding of the life  Read more...

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Reviews of first edition: "The author has certainly achieved his goal of providing anaccessible introduction to human drug metabolism" (The Annals ofPharmacotherapy, June 2006) "Armed with the Read more...

 
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