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Human fetal tissue transplantation

著者: Niranjan Bhattacharya; Phillip G Stubblefield
出版商: London ; New York : Springer, ©2013.
版本/格式:   电子图书 : 文献 : 英语查看所有的版本和格式
数据库:WorldCat
提要:
Over the past decade there have been major advances in the field of regenerative medicine with the promise to bring to reality, cures for debilitating diseases such as diabetes, heart failure, and Parkinson's disease. Cellular products from a variety of sources are being evaluated for their ability to replace damaged tissue.Fetal tissues consist of stem cells and progenitor cells which have undergone initial  再读一些...
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类型/形式: Electronic books
材料类型: 文献, 互联网资源
文件类型: 互联网资源, 计算机文档
所有的著者/提供者: Niranjan Bhattacharya; Phillip G Stubblefield
ISBN: 9781447141716 1447141717
OCLC号码: 828856529
描述: 1 online resource (xxix, 462 p.) : ill. (some col.)
内容: Part I: The Ideas Behind This Book --
Alternatives of Human Organ/Tissue Transplantation --
Fetomaternal Cell Trafficking: A Window into the Long-Term Health Effects of Treating Disease with Fetal Cell/Tissue Transplants? --
Part II: Basic Science and the Unique Aspect of Fetal Growth and Maturation --
Embryology of Fetal Tissue --
Three-Dimensional Culture of Fetal Mouse, Rat, and Porcine Hepatocytes --
Response of Fetal and Adult Cells to Growth Factors --
Accommodation and the Fetus --
Wharton's Jelly-Derived Mesenchymal Stromal Cells as Immunoregulatory Cells --
Pluripotent Stem Cells of the Mammalian Early Embryo --
Stem Cells in Fetal Tissue (The Kidney as a Model) --
Potential Therapeutic Applications of Placental-Derived Stem Cells to Combat Tissue Inflammation and Fibrosis --
Part III: Fetal Cell Transplant Experiments in Animal and Human Systems --
Experiences with In Utero Transplantation of Mesenchymal Stem Cells --
In Utero Hematopoietic Stem Cell Transplantation for Congenital Disorders --
Tissue and Progenitor Cell Transplantation for the Management of Pituitary Disorders: From Harvey Cushing to the Next Frontier --
Fetal Cell Therapy and Tissue Engineering for Musculoskeletal Tissues --
Cell Therapy for Parkinson's Disease --
Transplantation of Human Fetal Liver Cells into Children or Human Fetuses --
Fetal Liver Cell Transplantation --
Human Pancreatic Progenitors: Implications for Clinical Transplantation in Diabetes --
Amniotic Fluid Cell Therapy to Relieve Disc-Related Low Back Pain and Its Efficacy Comparison with Long-Acting Steroid Injection --
Human Neural Stem Cell Transplants in Neurological Disorders: Current Trends and Future Options --
Umbilical Cord Stem Cells for Pancreatic Regenerative Medicine --
Maturation of the Human Fetal Pancreas: A Lesson for Embryonic Stem Cell Differentiation as a Therapy for Diabetes --
Part IV: Fetal Tissue Transplant Experiments in Animal and Human Systems --
Fetal Neural Tissue Transplantation for Spinal Cord Injury Repair --
Fetal Lung Tissue Transplant at a Heterotopic Site in Common Chronic Inflammatory Diseases of the Airways: A Study of 11 Cases --
Treatment by Human Fetal Neuronal Tissue Transplant at a Heterotopic Site in the Axilla in Case of Motor Neuron Disease: A Report of Two Cases --
Adjuvant Role of Human Heterotopic Fetal Kidney Tissue Transplant in Reversing the Visible Parameters of Chronic Renal Diseases: A Preliminary Report of 9 Cases --
Treatment by Human Fetal Neuronal Tissue Transplant from Brain and Spinal Cord at Heterotopic Site in Axilla in Case of Posttraumatic Quadriplegia: A Report of Two Cases --
Fetal Liver Tissue Transplant in Alcoholic Fatty Degeneration of the Liver: A Study of 13 Cases --
Human Heterotopic Fetal Cardiac Tissue Transplant in Patients with Varying Degrees of Cardiomyopathy with Ischemic Heart Disease and Diabetes Mellitus: A Report of 7 Cases --
A Study and Follow-Up (1999-2012) of Fetal Midbrain Tissue Transplant (Iatrogenic Chimera) at a Heterotopic Site in Axilla as a Treatment Support in Cases of Adult Idiopathic Parkinsonism Patients --
Growing Organs for Transplantation from Embryonic Precursor Tissues --
Part V: Fetal Organ Transplant Experiments in Animal and Human Systems --
Fetal Thymus Transplantation in DiGeorge Syndrome --
Clinical Improvement After First-Trimester Fetal Whole Pancreas Transplant at a Heterotopic Site in Uncontrolled Diabetes with Varying Degrees of Skin Ulceration of the Leg and Emaciation --
Experience with Human Fetal Thymus Transplantation: In a Heterotopic Site in Patients with Advanced Lymphoma and Leukopenia --
Human Fetal Adrenal Transplant at Heterotopic Site as an Adjuvant for Treatment of Excruciating Pain in Cases of Arthritides --
Part VI: Biobanking --
Biobanking and Cryopreservation of Obstetrical Cell Sources for Cardiovascular Tissue Engineering: Implications for Future Therapies --
Part VII: Ethics of Fetal Tissue Transplant --
Of Bioethics, Stem Cells, and Tissue Transplants.
责任: Niranjan Bhattacharya, Phillip Stubblefield, editors.

摘要:

This book reviews pioneering research in fetal tissue transplant, including transplant of healthy fetal tissue into mature patients and hosts with genetic disease. Covers technique, donor-host  再读一些...

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    schema:description "Over the past decade there have been major advances in the field of regenerative medicine with the promise to bring to reality, cures for debilitating diseases such as diabetes, heart failure, and Parkinson's disease. Cellular products from a variety of sources are being evaluated for their ability to replace damaged tissue.Fetal tissues consist of stem cells and progenitor cells which have undergone initial commitment with varying states of differentiation. Stem cells from fetal tissues may also have a greater proliferative potential than their adult counterparts. In addition, fetal derived stem and progenitor cells are immunologically naive and some sources of fetal cells, eg cord blood, have been shown to be capable of crossing greater HLA mismatching resulting in less rejection and decreased immune mediated toxicities. Given the increasing focus on HES and advances in our basic knowledge of regenerative medicine it is an appropriate time to review the biology and use of fetal tissues.Human Fetal Tissue Transplantation is a timely publication that provides details of many aspects of the potential use of fetal tissues for therapeutic applications. As many tissues are wasted on a daily basis it appropriate to raise discussion on how to maximize access to discard tissue and at the same time engage in discussion of the ethics associated with fetal tissue procurement and clinical use." ;
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