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Human Gene Therapy: Current Opportunities and Future Trends

Author: Gabor M Rubanyi; Seppo Ylä-Herttuala
Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 2003.
Series: Ernst Schering Research Foundation workshop, 43.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
Advances in genetics, molecular biology and gene delivery technologies in recent years have lead to new gene therapy strategies to treat a variety of diseases. This book gives a comprehensive overview of the present status and future directions of gene delivery systems and therapeutic strategies for the clinical application of gene therapy in cancer, cardiovascular and central nervous system diseases. Stem  Read more...
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Genre/Form: Electronic books
Congresses
Additional Physical Format: Print version:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Gabor M Rubanyi; Seppo Ylä-Herttuala
ISBN: 9783662053522 3662053527 3540004130 9783540004134
OCLC Number: 851387542
Description: 1 online resource (xv, 256 pages).
Contents: 1 The Future of Gene Therapy --
I Cardiovascular Diseases --
2 Angiogenesis Clinical Trials --
3 AAV Vectors, the Future Workhorse of Human Gene Therapy --
4 Nonviral Vectors for Cardiovascular Gene Delivery --
5 Gene Therapy for Coronary Artery Disease: Preclinical and Initial Clinical Results with Intracoronary Administration of Ad5FGF-4 --
II Cancer --
6 Cancer Gene Therapy: Present Status and Future Directions --
7 Oncolytic Virotherapy as a Novel Treatment Platform for Cancer --
8 Adenovirus Retargeting and Systemic Delivery --
III CNS Diseases --
9 CNS Diseases Amenable to Gene Therapy --
10 Molecular Therapies for the Nervous System and Skeletal Muscle --
11 Lentivirus: A Vector for Nervous System Applications --
IV Novel Technologies --
12 Endothelial Progenitor Cells for Neovascularization --
13 Therapeutic Aptamers and Antidotes: A Novel Approach to Safer Drug Design --
14 Plasmid-Based Gene Transfer and Antiprogestin-Controllable Transgene Expression --
Previous Volumes Published in This Series.
Series Title: Ernst Schering Research Foundation workshop, 43.
Responsibility: edited by Gabor M. Rubanyi, Seppo Ylä-Herttuala.

Abstract:

Advances in genetics, molecular biology and gene delivery technologies in recent years have led to new gene therapy strategies for treatment of a variety of diseases.  Read more...

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