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Hypoxia, Metabolic Acidosis, and the Circulation

Author: Allen I Arieff
Publisher: New York, NY : Springer New York, 1992.
Series: Clinical physiology series.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
In recent years, there has been a wealth of new information on the physiological and biochemical consequences of hypoxia, or low blood levels of oxygen. This new volume discusses the implications of these new findings on the pathophysiology, development, and treatment of hypoxic metabolic acidosis. The volume is part of the Clinical Physiology series sponsored by the American Physiological Society, and is based on a  Read more...
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Details

Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Allen I Arieff
ISBN: 9781461475422 1461475422
OCLC Number: 852788503
Description: 1 online resource (232 pages).
Contents: From the Contents: Circulatory Regulation during Hypoxia and Hypercapnia --
Regulation of Myocardial Blood Flow and Oxygen Delivery during Hypoxia --
Acid-Base Status and Blood Lactate at Extreme Altitude --
Effects of Ischemia, Hypoxia, and Acidosis on Cardiac Systolic and Diastolic Function, and Glycolytic Metabolism in Normal and Hypertrophied Hearts.
Series Title: Clinical physiology series.
Responsibility: edited by Allen I. Arieff.

Abstract:

In recent years, there has been a wealth of new information on the physiological and biochemical consequences of hypoxia, or low blood levels of oxygen. This new volume discusses the implications of these new findings on the pathophysiology, development, and treatment of hypoxic metabolic acidosis. The volume is part of the Clinical Physiology series sponsored by the American Physiological Society, and is based on a FASEB symposium held in May 1988. Hypoxia was once thought to affect organs in a similar manner, but it is now known that each is affected differently. The author shows how hypoxia and metabolic acidosis affect the heart, lungs, blood vessels and other organs at the cellular level, the tissue level, and finally, at the level of the entire organ. The book then proceeds to a description of the situations in which hypoxic metabolic acidosis develops, such as during high altitude exposure, cardiac arrest, and lactic acidosis. The last few chapters give an overview of treatment. Traditional therapy has consisted largely of the intravenous administration of sodium bicarbonate. This method has come under increasing scrutiny however, and the range of problems associated with the use of sodium bicarbonate is examined fully. Newer alternative agents for managing hypoxic acidosis are reviewed as well. This up-to-date review of hypoxia and metabolic acidosis should be of interest to physiologists, internists, cardiologists, chest physicians, anesthesiologists, and intensive care specialists.

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