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IgE and anti-IgE therapy in asthma and allergic disease

Author: Robert B Fick; Paula M Jardieu
Publisher: New York : Marcel Dekker, ©2002.
Series: Lung biology in health and disease, v. 164.
Edition/Format:   Print book : EnglishView all editions and formats
Summary:

Exploring the role of Immunoglobulin-E (IgE) in human disease. This book summarizes research on the mechanisms and utilization of anti-IgE therapeutics in the treatment of IgE-mediated allergic  Read more...

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Document Type: Book
All Authors / Contributors: Robert B Fick; Paula M Jardieu
ISBN: 0824706633 9780824706630
OCLC Number: 48958620
Description: xxv, 542 pages : illustrations ; 23 cm.
Contents: 1. Introduction / S.G.O. Johansson --
2. Serum IgE distributions in normal and asthmatic subjects / Chantal Matkin Dolan [and others] --
3. Understanding the binding of IgE to its high-affinity receptor and to an anti-IgE antibody / Leonard G. Presta and Robert L. Shields --
4. Mediator release from basophils and mast cells and its relationship to FceRI expression and IgE-suppressing therapies / Donald W. MacGlashan [and others] --
5. Expression of IgE receptors on eosinophils / David Dombrowicz, André Capron, and Monique Capron --
6. Eosinophil IgE receptors : controversy and consensus / Hirohito Kita and Cheryl R. Adolphson --
7. Murine models of asthma : caveats and conclusions on the contribution of IgE and mast cells to allergic inflammation, airway hyperresponsiveness, and airflow obstruction / Jeffrey S. Tepper and Daniel B. Tumas --
8. Role of IgE in asthma : pathogenesis and novel therapeutic strategies / James Laurence Lordan, Stephen T. Holgate, and Ian Sayers --
9. IgE-mediated response to allergen in the bronchoprovocation laboratory / Louis-Philippe Boulet and Donald W. Cockcroft --
10. Pathophysiology of the airway response to inhaled allergen in asthmatic subjects : role of IgE / John V. Fahy --
11. Efficacy and safety of xolair anti-IgE monoclonal antibody in adult asthmatics / Robert B. Fick, Jr., and W. James Metzger --
12. The role of IgE in pediatric asthma / Henry Milgrom and Charles Johnson --
13. Anti-inflammatory activities of omalizumab (xolair), a recombinant humanized monoclonal antibody binding IgE / Robert B. Fick, Jr. --
14. Pulmonary delivery of anti-IgE : rationale for topical delivery to the airway / Theresa D. Sweeney [and others] --
15. Treatment of seasonal allergic rhinitis / Thomas B. Casale and Patricia W. Rohane --
16. Anti-IgE and allergic skin diseases / Michaël F. Hofer and Donald Y.M. Leung --
17. Role of IgE and food allergens / Ricki M. Helm and A. Wesley Burks --
18. Role of IgE in allergic bronchopulmonary aspergillosis / Priscilla S.A. Sarinas and Rajinder K. Chitkara --
19. IgE and its role in parasitic helminth infection : implications for anti-IgE-based therapies / Philip J. Cooper and Thomas B. Nutman --
20. The rise of antibodies as therapeutics / Maureen P. Quan and Paul Carter.
Series Title: Lung biology in health and disease, v. 164.
Responsibility: edited by Robert B. Fick, Jr., Paula M. Jardieu.
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