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Immunotherapy in asthma

Author: Jean Bousquet; Hans Yssel
Publisher: New York, NY : M. Dekker, ©1999.
Series: Lung biology in health and disease, v. 136.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
"This massive reference thoroughly analyzes the mechanisms implicated in the pathophysiology of asthma, such as T helper lymphocyte subsets, various extrinsic and intrinsic factors, and IgE receptor expression - reviewing current concepts in immunotherapeutic approaches for the treatment of this and other allergic diseases." "Written by more than 80 internationally renowned pulmonary experts and allergic disease  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Immunotherapy in asthma.
New York, NY : M. Dekker, ©1999
(DLC) 99037341
(OCoLC)41712255
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Jean Bousquet; Hans Yssel
ISBN: 0585158568 9780585158563
OCLC Number: 44959503
Description: 1 online resource (xxvii, 669 pages) : illustrations.
Contents: Introduction / Claude Lenfant --
Part One. Mechanisms of Allergic Asthma --
Human T Helper Type 1 and Type 2 Subsets / Hans Yssel --
Mechanisms of Allergic Asthma : A Th2 Disease / Douglas S. Robinson, A. Barry Kay --
Mechanisms of Asthma : Asthma Is an Allergic Disease / Lisa M. Wheatley, Thomas A.E. Platts-Mills --
Inflammation and Airway Remodeling in Asthma / Jean Bousquet [and others] --
The Prognosis and Natural History of Asthma / Jorrit Gerritsen [and others] --
Part Two. Allergen-Specific Immunotherapy --
Allergen Immunotherapy : Therapeutic Vaccines for Allergic Diseases (WHO Position Paper, Executive Summary) / Jean Bousquet, Richard F. Lockey, Hans-Jorgen Malling --
Allergen-Specific Immunotherapy : New Strategies Using Recombinant Allergens / Alisa M. Smith, Martin D. Chapman --
Elimination of Allergens / Frederic de Blay [and others] --
Standardization of Allergens / Jean Bousquet, Francois-Bernard Michel --
Allergen-Specific Immunotherapy : Past and Present / Philip S. Norman --
Allergen-Specific Immunotherapy : Mechanisms of Immunotherapy / Jerome Pene, Jean Bousquet --
Objectives of Immunotherapy in Asthma / Anthony J. Frew --
Allergen-Specific Immunotherapy for Asthma : Metanalysis of Randomized Controlled Trials / Michael J. Abramson, Robert M. Puy, John M. Weiner --
Noninjective Immunotherapy : Present Knowledge and Experimental Evidence / Giovanni Passalacqua, Gian Enrico Senna, Giorgio Walter Canonica --
Pediatric Issues in Immunotherapy / Erkka Valovirta --
International Recommendations / Hans-Jørgen Malling --
Peptide-Mediated Immunomodulation as Therapy for Allergic Disorders / Nanna S. Kristensen, Hans Yssel, Jonathan R. Lamb --
Potential of Recombinant Allergens as Immunotherapeutic Agents for Allergy and Asthma / Shyam S. Mohapatra --
Molecular Characterization of Allergens, Their B-Cell Epitopes and Allergen-Specific Antibodies for Allergy Prevention and Treatment / Rudolf Valenta [and others] --
Tolerogenic Peptides : Clinical Experience in Allergy / Christopher F. Nicodemus, George Philip --
Manipulation of the Idiotypic Network : An Alternative Approach to Treat Allergic Asthma? / Yvan Boutin, Jacques Hebert --
The Use of Allergen-Specific Antibodies for Immunotherapy / Jean-Marie R. Saint-Remy --
Part Three. Regulation of IgE Inflammation --
Anti-Immunoglobulin E Therapy for Asthma / Pascal Demoly, Dany Jaffuel, Jean Bousquet --
Expression and Function of the High-Affinity Receptor for Immunoglobulin E in Asthma / Marie-Helene Jouvin, Jean-Pierre Kinet --
Factors Modulating Allergen-Induced Histamine Release : Fc-Receptors, Antibodies, and Allergens / Ronald van Ree --
Regulation of Immunoglobulin E--Mediated Inflammation by Soluble Fragments of the High-Affinity Immunoglobulin E Receptor / Brian J. Sutton, Hannah J. Gould --
Regulation of Immunoglobulin E Inflammation : Anti-Immunoglobulin E Autoantibodies / Beda M. Stadler --
Part Four. Non-Immunoglobulin E-Dependent Immunotherapy --
Non-Immunoglobulin E--Dependent Immunotherapy : Treatment of Asthma with Inhaled Interferon Gamma / Gideon Lack, Donald Y.M. Leung, Erwin W. Gelfand --
Role of Interleukin-5 in Eosinophil-Based Diseases / Francis M. Cuss [and others] --
Part Five. Prevention of Allergic Asthma : Is It Possible? --
Primary Prevention of Atopic Asthma : Prophylactic Strategies Based on Immunomodulation of Host Responses During Childhood / Patrick G. Holt --
Outdoor Air Pollution and Asthma / Erika von Mutius --
The Genetic Basis of Allergy and Asthma / Pamela J. Amelung, Eugene R. Bleecker --
Gene Therapy Strategies for Asthma / Pascal Demoly [and others].
Series Title: Lung biology in health and disease, v. 136.
Responsibility: edited by Jean Bousquet, Hans Yssel.

Abstract:

"This massive reference thoroughly analyzes the mechanisms implicated in the pathophysiology of asthma, such as T helper lymphocyte subsets, various extrinsic and intrinsic factors, and IgE receptor expression - reviewing current concepts in immunotherapeutic approaches for the treatment of this and other allergic diseases." "Written by more than 80 internationally renowned pulmonary experts and allergic disease specialists, Immunotherapy in Asthma discusses the efficacy of new medications ... examines the role of metachromatic cells, lymphocytes, macrophages, and other cell types present in bronchial biopsies ... presents basic topics such as the functional and phenotypic properties of Th1 and Th2 cells and their role in allergic disease and the regulation of IgE-mediated inflammatory responses ... addresses the deleterious effects of smoking and passive exposure to cigarette smoke in children and adults ... assesses differences and similarities between "intrinsic" and antigen-induced asthma ... describes the effects of immunogenic peptides on the cytokine production profile of allergen specific CD4 [superscript +] T cells ... explains the different clinical aspects of allergic responses, such as bronchial hyperreactivity and eosinophilic inflammation of the airways ... reviews the genetic basis of allergy, as well as risk factors for asthma ... explores oral, sublingual, local nasal, and local bronchial routes for noninjective immunotherapies ... evaluates various agents with modulatory effects on normal and pathogenic immune responses ... focuses on strategies for the prevention of childhood asthma ... and more."--Jacket.

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