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Improving the utility and translation of animal models for nervous system disorders : workshop summary

Author: Diana E Pankevich; Theresa M Wizemann; Bruce M Altevogt; Institute of Medicine (U.S.). Forum on Neuroscience and Nervous System Disorders,
Publisher: Washington, D.C. : The National Academies Press, [2013]
Edition/Format:   eBook : Document : Conference publication : EnglishView all editions and formats
Database:WorldCat
Summary:
Nervous system diseases and disorders are highly prevalent and substantially contribute to the overall disease burden. Despite significant information provided by the use of animal models in the understanding of the biology of nervous system disorders and the development of therapeutics; limitations have also been identified. Treatment options that are high in efficacy and low in side effects are still lacking for  Read more...
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Genre/Form: Congresses
Electronic books
Conference proceedings
Additional Physical Format: Print version:
Improving the utility and translation of animal models for nervous system disorders.
Washington, D.C. : National Academies Press, [2013]
(DLC) 2013427677
(OCoLC)846679526
Material Type: Conference publication, Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Diana E Pankevich; Theresa M Wizemann; Bruce M Altevogt; Institute of Medicine (U.S.). Forum on Neuroscience and Nervous System Disorders,
ISBN: 9780309266338 0309266335 9780309266345 0309266343
OCLC Number: 827359047
Notes: Title from PDF title page.
Description: 1 online resource (1 PDF file (xi, 97 pages)) : illustrations.
Contents: Introduction and overview --
Evaluation of current animal models --
Translation from animal models to the clinic: case examples from neuroscience research --
Perspectives on standardization --
Perspectives on corresponding animal and clinical endpoints --
Addressing the translational disconnect --
Summary of workshop topics.
Responsibility: Diana E. Pankevich, Theresa M. Wizemann, and Bruce M. Altevogt, rapporteurs ; Forum on Neuroscience and Nervous System Disorders, Board on Health Sciences Policy, Institute of Medicine of the National Academies.
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Abstract:

Identifies methods to facilitate development of corresponding animal and clinical endpoints, indentifies methods that would maximize bidirectional translation between basic and clinical research and  Read more...

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