skip to content
In vivo footprinting Preview this item
ClosePreview this item
Checking...

In vivo footprinting

Author: Iain L Cartwright
Publisher: Greenwich, Conn. : JAI Press, ©1997.
Series: Advances in molecular and cell biology, v. 21.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
The revolution in biological research initiated by the demonstration that particular DNA molecules could be isolated, recombined in novel ways, and conveniently replicated to high copy number in vivo for further study, that is, the recombinant DNA era, has spawned many additional advances, both methodological and intellectual, that have enhanced our understanding of cellular processes to an astonishing degree. As  Read more...
Rating:

(not yet rated) 0 with reviews - Be the first.

Subjects
More like this

Find a copy online

Links to this item

Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...

Details

Genre/Form: Electronic books
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Iain L Cartwright
ISBN: 0762301457 9780762301454
OCLC Number: 464825532
Description: 1 online resource (xii, 209 pages) : illustrations.
Contents: Contents. List of Contributors. Preface (I.L. Cartwright). A Perspective on In Vivo Footprinting (M. Nenoi and I.L. Cartwright). Genomic Sequencing by Template Purification: Principles and mapping of Protein-Bound and Single-Stranded Sequences in Vivo (J. Mirkowitch). Polymerase Chain Reaction-Aided Genomic Footprinting: Principles and Application (A.D. Riggs and G.P. Pfeifer). In Vivo Footprinting of the Interaction of Proteins with DNA and RNA (T. Grange, G. Rigaud, E. Bertrand, M. Fromont-Racine, M.L. Espinals, J. Roux, and R. Pictet). Characterization of In Vivo DNA-Protein Interactions in the Transcriptional Regulation of the Human Heat Shock Genes (L. Sistonen and R.I. Morimoto). Analysis of the Gata-1 Gene Promoter and Globin Locus Control Region Elements by In Vivo Footprinting 9E.C. Strauss and S.H. Orkin). Anazlyzing Hormone Regulation of Transcription by Genomic Footprinting (A. Reik, G. Schutz and A.F. Stewart). Photofootprinting Studies of SV40 Minichromosomes In Vivo (G.A. Grossman and M.M. Becker). Index.
Series Title: Advances in molecular and cell biology, v. 21.
Responsibility: Iain L. Cartwright.

Abstract:

The revolution in biological research initiated by the demonstration that particular DNA molecules could be isolated, recombined in novel ways, and conveniently replicated to high copy number in vivo  Read more...

Reviews

User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

Be the first.

Similar Items

Related Subjects:(2)

Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Linked Data


Primary Entity

<http://www.worldcat.org/oclc/464825532> # In vivo footprinting
    a schema:CreativeWork, schema:Book, schema:MediaObject ;
    library:oclcnum "464825532" ;
    library:placeOfPublication <http://id.loc.gov/vocabulary/countries/ctu> ;
    library:placeOfPublication <http://experiment.worldcat.org/entity/work/data/42392110#Place/greenwich_conn> ; # Greenwich, Conn.
    schema:about <http://id.worldcat.org/fast/886597> ; # DNA probes
    schema:about <http://id.worldcat.org/fast/940086> ; # Genetic regulation
    schema:about <http://dewey.info/class/572.865/e23/> ;
    schema:bookFormat schema:EBook ;
    schema:contributor <http://viaf.org/viaf/3641148947910254950005> ; # Iain L. Cartwright
    schema:copyrightYear "1997" ;
    schema:datePublished "1997" ;
    schema:description "The revolution in biological research initiated by the demonstration that particular DNA molecules could be isolated, recombined in novel ways, and conveniently replicated to high copy number in vivo for further study, that is, the recombinant DNA era, has spawned many additional advances, both methodological and intellectual, that have enhanced our understanding of cellular processes to an astonishing degree. As part of the subsequent outpouring of information, research exploring the mechanisms of gene regulation, both in prokaryotes and eukaryotes (but particularly the latter), has been particularly well represented. Although no one technical approach can be said to have brought the filed to its current level of sophistication, the ability to map the interactions of trans-acting factors with their DNA recognition sequences to a high level of precision has certainly been one of the more important advances. This "footprinting" approach has become almost ubiquitous in gene regulatory studies; however, it is in its "in vivo" application that ambiguities, confusions, and inconsistencies that may arise from a purely "in vitro"--Based approach can often be resolved and placed in their proper perspective. Put more simply, that an interaction can be demonstrated to occur between purified factors and a particular piece of DNA in a test tube does not, of course, say anything regarding whether such interactions are occurring in vivo. The ability to probe for such interactions as they occur inside cells, with due attention paid to the relevant developmental stage, or to the tissue specificity of the interaction being probed, has made in vivo footprinting approach an invaluable adjunct to the "gene jockey's" arsenal of weapons."@en ;
    schema:exampleOfWork <http://worldcat.org/entity/work/id/42392110> ;
    schema:genre "Electronic books"@en ;
    schema:inLanguage "en" ;
    schema:isPartOf <http://experiment.worldcat.org/entity/work/data/42392110#Series/advances_in_molecular_and_cell_biology> ; # Advances in molecular and cell biology ;
    schema:name "In vivo footprinting"@en ;
    schema:productID "464825532" ;
    schema:publication <http://www.worldcat.org/title/-/oclc/464825532#PublicationEvent/greenwich_conn_jai_press_1997> ;
    schema:publisher <http://experiment.worldcat.org/entity/work/data/42392110#Agent/jai_press> ; # JAI Press
    schema:url <http://dproxy.library.dc-uoit.ca/login?url=https://www.sciencedirect.com/science/bookseries/15692558/21> ;
    schema:url <http://dproxy.library.dc-uoit.ca/login?url=https://www.sciencedirect.com/science/book/9780762301454> ;
    schema:url <http://www.sciencedirect.com/science/book/9780762301454> ;
    schema:url <http://www.sciencedirect.com/science/bookseries/15692558/21> ;
    schema:workExample <http://worldcat.org/isbn/9780762301454> ;
    wdrs:describedby <http://www.worldcat.org/title/-/oclc/464825532> ;
    .


Related Entities

<http://dproxy.library.dc-uoit.ca/login?url=https://www.sciencedirect.com/science/book/9780762301454>
    rdfs:comment "eBook available for Durham College via Elsevier. Click link to access" ;
    .

<http://dproxy.library.dc-uoit.ca/login?url=https://www.sciencedirect.com/science/bookseries/15692558/21>
    rdfs:comment "eSeries Volume available for Durham College via Elsevier. Click link to access" ;
    .

<http://experiment.worldcat.org/entity/work/data/42392110#Place/greenwich_conn> # Greenwich, Conn.
    a schema:Place ;
    schema:name "Greenwich, Conn." ;
    .

<http://experiment.worldcat.org/entity/work/data/42392110#Series/advances_in_molecular_and_cell_biology> # Advances in molecular and cell biology ;
    a bgn:PublicationSeries ;
    schema:hasPart <http://www.worldcat.org/oclc/464825532> ; # In vivo footprinting
    schema:name "Advances in molecular and cell biology ;" ;
    .

<http://id.worldcat.org/fast/886597> # DNA probes
    a schema:Intangible ;
    schema:name "DNA probes"@en ;
    .

<http://id.worldcat.org/fast/940086> # Genetic regulation
    a schema:Intangible ;
    schema:name "Genetic regulation"@en ;
    .

<http://viaf.org/viaf/3641148947910254950005> # Iain L. Cartwright
    a schema:Person ;
    schema:familyName "Cartwright" ;
    schema:givenName "Iain L." ;
    schema:name "Iain L. Cartwright" ;
    .

<http://worldcat.org/isbn/9780762301454>
    a schema:ProductModel ;
    schema:isbn "0762301457" ;
    schema:isbn "9780762301454" ;
    .


Content-negotiable representations

Close Window

Please sign in to WorldCat 

Don't have an account? You can easily create a free account.