RT Journal DB /z-wcorg/ DS http://worldcat.org ID 441451511 LA English T1 Infectious insanities, surgical solutions: Bayard Taylor Holmes, dementia praecox and laboratory science in early 20th-century America. Part 1 A1 Noll, Richard, PB Sage Publications YR 2006 SN 0957-154X JF History of Psychiatry VO 17 IS 2 SP 183 OP 204 AB After his 17-year-old son suddenly developed a chronic psychotic illness in 1905, Bayard Taylor Holmes (1852-1924), a Chicago physician and surgeon with no psychiatric training, conducted both library and laboratory research on dementia praecox, as described in Part 1 of this two-part study. By late 1915 he believed he had found support for a focal infection theory of its aetiology - an ergot-like toxaemia caused by faecal stasis in the caecum. Holmes was also the editor of what is believed to be the first medical journal named after a psychiatric disorder: Dementia Praecox Studies. Part 2 will describe Holmes’ adoption of a rational therapy (using it first on his son, who died), and his founding of a Psychiatric Research Laboratory.