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International review of experimental pathology. Volume 32, Molecular cell pathology

Author: G W Richter; Kim Solez
Publisher: San Diego : Academic Press, Inc., [1991] ©1991
Edition/Format:   eBook : Document : EnglishView all editions and formats
Summary:
International Review of Experimental Pathology, Volume 32: Molecular Cell Pathology discusses the applications and practical value of in situ hybridization; the interactions between endothelial cells and the cells of the immune system; and the molecular biology of cytokine effects on vascular endothelial cells. The text also describes the interphase nucleolar organizer regions in cancer cells; the disease  Read more...
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Genre/Form: Electronic books
Additional Physical Format: Print version:
Richter, G.W.
Molecular Cell Pathology : Molecular Cell Pathology.
Burlington : Elsevier Science, ©1991
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: G W Richter; Kim Solez
ISBN: 9781483218410 1483218414
OCLC Number: 896844750
Description: 1 online resource (297 pages) : illustrations
Contents: Front Cover; Molecular Cell Pathology; Copyright Page ; Table of Contents; Contributors; Chapter 1. Applications of in Situ Hybridization; I. Introduction; II. Methodology; III. Applications; IV. Practical Value for Histopathology; References; Chapter 2. Interactions between Endothelial Cells and the Cells of the Immune System; I. Introduction; II. Interactions between Endothelial Cells and Immune System Cells in the Control of Coagulation; III. Lymphocyte/Endothelial Cell Interactions in Lymphocyte Recirculation. IV. Interactions between Endothelial Cells and Immune System Cells in the Regulation of Mononuclear Cell Migration into Inflammatory LesionsV. The Role of Cytokines in the Activation of Endothelial Cells at Sites of Inflammation; VI. The Effects of Cytokines on Endothelial Cell Expression of MHC Antigens and Their Possible Role in Endothelial Cell Antigen Presentation; VII. Endothelial Cell Proliferation and Angiogenesis; VIII. Effects of Endothelial Cell Products on the Function of Immune System Cells; IX. Conclusions; References. Chapter 3. Molecular Biology of Cytokine Effects on Vascular Endothelial CellsI. Introduction; II. Molecular Basis of Cytokine Responsiveness of Vascular Endothelial Cells; III. Regulation and Induction of Endothelial Gene Expression by Cytokines; IV. Endothelial Gene Expression in in Vivo and in Situ Hybridization; V. Future Directions of Research; References; Chapter 4. Interphase Nucleolar Organizer Regions in Cancer Cells; I. Introduction; II. Silver Staining Techniques for the Visualization of NORs; III. General Factors Influencing the Specificity of the Silver Stain for NORs. IV. Molecular Components Responsible for Silver StainingV. NORs Not Stained by the Ag-NOR Techniques; VI. Localization of NORs in Interphase Nucleoli; VII. Structure and Function of Interphase NORs; VIII. Nucleolar Morphology; IX. Interphase NOR Distribution; X. Distribution of Silver-Stained Interphase NORs in Neoplastic Cells; XI. Is the High Number of Interphase NORs a Peculiar Feature of Cancer Cells?; XII. Relationship between Interphase NOR Distribution and Neoplastic State of the Cell; XIII. Structural Changes of Ribosomal Genes in Cells Stimulated to Proliferate; References. Chapter 5. Antineutrophil Cytoplasmic Autoantibodies: Disease Associations, Molecular Biology, and PathophysiologyI. Introduction; II. Clinical and Pathologic Spectrum of ANCA-Associated Diseases; III. Elucidation of ANCA Antigen Specificity; IV. Pathogenetic Potential of ANCAs; V. Conclusion; References; Chapter 6. Apoptosis: Mechanisms and Roles in Pathology; I. Introduction; II. Morphology; III. Mechanisms; IV. Roles in Pathology; V. Conclusions; References; Chapter 7. Molecular Events in Measles Virus Infection of the Central Nervous System; I. Introduction.
Responsibility: edited by G.W. Richter, Department of Pathology, University of Rochester Medical Center, Rochester, New York, Kim Solez, Department of Pathology, Faculty of Medicine, University of Alberta, Edmonton, Alberta.

Abstract:

The articles in this volume describe problems and methods relevant to a better understanding of the pathogenesis of several diseases. They focus on experimental pathology at sub-cellular levels, in  Read more...

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