skip to content
Intrinsic immunity Preview this item
ClosePreview this item
Checking...

Intrinsic immunity

Author: Bryan Cullen
Publisher: Berlin ; New York : Springer, ©2013.
Series: Current topics in microbiology and immunology, v.371.
Edition/Format:   eBook : Document : EnglishView all editions and formats
Database:WorldCat
Summary:
Recent research has focused attention on the importance of intrinsic antiviral immunity, i.e. immunity mediated by factors that are constitutively expressed in many cells. In this volume, leading experts provide a comprehensive overview of this relatively new and rapidly evolving field. They cover intrinsic proteinaceous antiviral immune effectors, such as the APOBEC3 and TRIM protein families as well as Tetherin  Read more...
Rating:

(not yet rated) 0 with reviews - Be the first.

Subjects
More like this

 

Find a copy online

Links to this item

Find a copy in the library

&AllPage.SpinnerRetrieving; Finding libraries that hold this item...

Details

Genre/Form: Electronic books
Additional Physical Format: Printed edition:
Material Type: Document, Internet resource
Document Type: Internet Resource, Computer File
All Authors / Contributors: Bryan Cullen
ISBN: 9783642377655 3642377653 3642377645 9783642377648
OCLC Number: 845039058
Notes: Includes index.
Description: 1 online resource.
Contents: The APOBEC3 Family of Retroelement Restriction Factors / Eric W. Refsland, Reuben S. Harris --
Inhibition of Retroviral Replication by Members of the TRIM Protein Family / Adam J. Fletcher, Greg J. Towers --
The Antiviral Activities of Tetherin / Stuart J. D. Neil --
Restriction of Retroviral Infection of Macrophages / Mark Sharkey --
Rapid Adversarial Co-Evolution of Viruses and Cellular Restriction Factors / Welkin E. Johnson --
RNA Interference-Mediated Intrinsic Antiviral Immunity in Plants / György Szittya, József Burgyán --
RNA Interference-Mediated Intrinsic Antiviral Immunity in Invertebrates / Arabinda Nayak, Michel Tassetto, Mark Kunitomi, Raul Andino --
Roles of MicroRNAs in the Life Cycles of Mammalian Viruses / Eva Gottwein --
Interplay Between DNA Tumor Viruses and the Host DNA Damage Response / Karyn McFadden, Micah A. Luftig.
Series Title: Current topics in microbiology and immunology, v.371.
Responsibility: Bryan R. Cullen, editor.

Abstract:

Recent research has focused attention on the importance of intrinsic antiviral immunity, i.e. immunity mediated by factors that are constitutively expressed in many cells. In this volume, leading experts provide a comprehensive overview of this relatively new and rapidly evolving field. They cover intrinsic proteinaceous antiviral immune effectors, such as the APOBEC3 and TRIM protein families as well as Tetherin and SAMHD1, which were initially discovered by researchers studying HIV-1. Furthermore, the role of RNA interference in antiviral defense in plants and invertebrates, as well as the interplay between microRNAs and viruses in mammalian cells, are analysed. One chapter discusses how intrinsic immunity and viral countermeasures to intrinsic immune effectors drive both pathogen and host evolution, and finally the emerging evidence that DNA damage response proteins restrict infection by DNA viruses is highlighted.

Reviews

User-contributed reviews
Retrieving GoodReads reviews...
Retrieving DOGObooks reviews...

Tags

Be the first.
Confirm this request

You may have already requested this item. Please select Ok if you would like to proceed with this request anyway.

Linked Data


Primary Entity

<http://www.worldcat.org/oclc/845039058> # Intrinsic immunity
    a schema:CreativeWork, schema:Book, schema:MediaObject ;
    library:oclcnum "845039058" ;
    library:placeOfPublication <http://experiment.worldcat.org/entity/work/data/1214422375#Place/berlin> ; # Berlin
    library:placeOfPublication <http://id.loc.gov/vocabulary/countries/gw> ;
    library:placeOfPublication <http://dbpedia.org/resource/New_York_City> ; # New York
    schema:about <http://experiment.worldcat.org/entity/work/data/1214422375#Topic/science_life_sciences_anatomy_&_physiology> ; # SCIENCE / Life Sciences / Anatomy & Physiology
    schema:about <http://experiment.worldcat.org/entity/work/data/1214422375#Thing/virology> ; # Virology.
    schema:about <http://experiment.worldcat.org/entity/work/data/1214422375#Thing/biomedicine> ; # Biomedicine.
    schema:about <http://experiment.worldcat.org/entity/work/data/1214422375#Thing/molecular_medicine> ; # Molecular Medicine.
    schema:about <http://experiment.worldcat.org/entity/work/data/1214422375#Thing/medical_virology> ; # Medical virology.
    schema:about <http://experiment.worldcat.org/entity/work/data/1214422375#Thing/medicine> ; # Medicine.
    schema:about <http://experiment.worldcat.org/entity/work/data/1214422375#Topic/immunity_innate> ; # Immunity, Innate
    schema:about <http://experiment.worldcat.org/entity/work/data/1214422375#Thing/microbial_genetics> ; # Microbial genetics.
    schema:about <http://id.worldcat.org/fast/967949> ; # Immunogenetics
    schema:about <http://dewey.info/class/571.9648/e23/> ;
    schema:about <http://id.worldcat.org/fast/1024811> ; # Molecular immunology
    schema:about <http://experiment.worldcat.org/entity/work/data/1214422375#Thing/immunology> ; # Immunology.
    schema:about <http://experiment.worldcat.org/entity/work/data/1214422375#Thing/plant_diseases> ; # Plant diseases.
    schema:about <http://experiment.worldcat.org/entity/work/data/1214422375#Thing/plant_pathology> ; # Plant Pathology.
    schema:bookFormat schema:EBook ;
    schema:contributor <http://viaf.org/viaf/36978775> ; # Bryan Cullen
    schema:copyrightYear "2013" ;
    schema:datePublished "2013" ;
    schema:description "Recent research has focused attention on the importance of intrinsic antiviral immunity, i.e. immunity mediated by factors that are constitutively expressed in many cells. In this volume, leading experts provide a comprehensive overview of this relatively new and rapidly evolving field. They cover intrinsic proteinaceous antiviral immune effectors, such as the APOBEC3 and TRIM protein families as well as Tetherin and SAMHD1, which were initially discovered by researchers studying HIV-1. Furthermore, the role of RNA interference in antiviral defense in plants and invertebrates, as well as the interplay between microRNAs and viruses in mammalian cells, are analysed. One chapter discusses how intrinsic immunity and viral countermeasures to intrinsic immune effectors drive both pathogen and host evolution, and finally the emerging evidence that DNA damage response proteins restrict infection by DNA viruses is highlighted." ;
    schema:exampleOfWork <http://worldcat.org/entity/work/id/1214422375> ;
    schema:genre "Electronic books" ;
    schema:inLanguage "en" ;
    schema:isPartOf <http://worldcat.org/issn/0070-217X> ; # Current topics in microbiology and immunology,
    schema:isPartOf <http://experiment.worldcat.org/entity/work/data/1214422375#Series/current_topics_in_microbiology_and_immunology> ; # Current topics in microbiology and immunology ;
    schema:isSimilarTo <http://worldcat.org/entity/work/data/1214422375#CreativeWork/> ;
    schema:name "Intrinsic immunity" ;
    schema:productID "845039058" ;
    schema:publication <http://www.worldcat.org/title/-/oclc/845039058#PublicationEvent/berlin_new_york_springer_c2013> ;
    schema:publisher <http://experiment.worldcat.org/entity/work/data/1214422375#Agent/springer> ; # Springer
    schema:url <http://search.ebscohost.com/login.aspx?direct=true&scope=site&db=nlebk&db=nlabk&AN=581505> ;
    schema:url <http://swb.eblib.com/patron/FullRecord.aspx?p=1317009> ;
    schema:url <http://site.ebrary.com/id/10714368> ;
    schema:url <http://dx.doi.org/10.1007/978-3-642-37765-5> ;
    schema:url <http://public.eblib.com/choice/publicfullrecord.aspx?p=1317009> ;
    schema:workExample <http://worldcat.org/isbn/9783642377655> ;
    schema:workExample <http://worldcat.org/isbn/9783642377648> ;
    schema:workExample <http://dx.doi.org/10.1007/978-3-642-37765-5> ;
    wdrs:describedby <http://www.worldcat.org/title/-/oclc/845039058> ;
    .


Related Entities

<http://dbpedia.org/resource/New_York_City> # New York
    a schema:Place ;
    schema:name "New York" ;
    .

<http://experiment.worldcat.org/entity/work/data/1214422375#Series/current_topics_in_microbiology_and_immunology> # Current topics in microbiology and immunology ;
    a bgn:PublicationSeries ;
    schema:hasPart <http://www.worldcat.org/oclc/845039058> ; # Intrinsic immunity
    schema:name "Current topics in microbiology and immunology ;" ;
    .

<http://experiment.worldcat.org/entity/work/data/1214422375#Thing/medical_virology> # Medical virology.
    a schema:Thing ;
    schema:name "Medical virology." ;
    .

<http://experiment.worldcat.org/entity/work/data/1214422375#Thing/microbial_genetics> # Microbial genetics.
    a schema:Thing ;
    schema:name "Microbial genetics." ;
    .

<http://experiment.worldcat.org/entity/work/data/1214422375#Thing/molecular_medicine> # Molecular Medicine.
    a schema:Thing ;
    schema:name "Molecular Medicine." ;
    .

<http://experiment.worldcat.org/entity/work/data/1214422375#Thing/plant_diseases> # Plant diseases.
    a schema:Thing ;
    schema:name "Plant diseases." ;
    .

<http://experiment.worldcat.org/entity/work/data/1214422375#Thing/plant_pathology> # Plant Pathology.
    a schema:Thing ;
    schema:name "Plant Pathology." ;
    .

<http://experiment.worldcat.org/entity/work/data/1214422375#Topic/immunity_innate> # Immunity, Innate
    a schema:Intangible ;
    schema:name "Immunity, Innate" ;
    .

<http://experiment.worldcat.org/entity/work/data/1214422375#Topic/science_life_sciences_anatomy_&_physiology> # SCIENCE / Life Sciences / Anatomy & Physiology
    a schema:Intangible ;
    schema:name "SCIENCE / Life Sciences / Anatomy & Physiology" ;
    .

<http://id.worldcat.org/fast/1024811> # Molecular immunology
    a schema:Intangible ;
    schema:name "Molecular immunology" ;
    .

<http://id.worldcat.org/fast/967949> # Immunogenetics
    a schema:Intangible ;
    schema:name "Immunogenetics" ;
    .

<http://viaf.org/viaf/36978775> # Bryan Cullen
    a schema:Person ;
    schema:familyName "Cullen" ;
    schema:givenName "Bryan" ;
    schema:name "Bryan Cullen" ;
    .

<http://worldcat.org/isbn/9783642377648>
    a schema:ProductModel ;
    schema:description "print" ;
    schema:isbn "3642377645" ;
    schema:isbn "9783642377648" ;
    .

<http://worldcat.org/isbn/9783642377655>
    a schema:ProductModel ;
    schema:description "electronic bk." ;
    schema:isbn "3642377653" ;
    schema:isbn "9783642377655" ;
    .

<http://worldcat.org/issn/0070-217X> # Current topics in microbiology and immunology,
    a bgn:PublicationSeries ;
    schema:hasPart <http://www.worldcat.org/oclc/845039058> ; # Intrinsic immunity
    schema:issn "0070-217X" ;
    schema:name "Current topics in microbiology and immunology," ;
    .


Content-negotiable representations

Close Window

Please sign in to WorldCat 

Don't have an account? You can easily create a free account.