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An introduction to medicinal chemistry

Author: Graham L Patrick; John Spencer
Publisher: New York : Oxford University Press, 2009.
Edition/Format:   Book : English : 4th edView all editions and formats
Database:WorldCat
Summary:

Assuming minimum background knowledge, the book develops an understanding of the molecular function of drugs and how they interact with the body, before exploring drug discovery and development. It  Read more...

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Document Type: Book
All Authors / Contributors: Graham L Patrick; John Spencer
ISBN: 9780199234479 0199234477
OCLC Number: 244062812
Description: xxii, 752 p. : ill. (some col.) ; 27 cm.
Contents: Drugs and drug targets : an overview --
Proteins : structure and function --
Enzymes : structure and function --
Receptors : structure and function --
Receptors and signal transduction --
Nucleic acids : structure and function --
Enzymes as drug targets --
Receptors as drug targets --
Nucleic acids as drug targets --
Miscellaneous drug targets --
Pharmacokinetics and related topics --
Drug discovery : finding a lead --
Drug design : optimizing target interactions --
Drug design : optimizing access to the target --
Getting the drug to market --
Combinatorial and parallel synthesis --
Computers in medicinal chemistry --
Quantitative structure-activity relationships --
Antibacterial agents --
Antiviral agents --
Anticancer agents --
Cholinergics, anticholinergics, and anticholinesterases --
Drugs acting on the adrenergic nervous system --
Opioid analgesics --
Antiulcer agents.
Responsibility: Graham L. Patrick ; with a chapter on combinatorial and parallel synthesis ; co-authored by John Spencer.
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